{"id":"W4220831801","doi":"10.3390/cancers14061577","title":"At the Intersection of Cardiology and Oncology: TGFβ as a Clinically Translatable Therapy for TNBC Treatment and as a Major Regulator of Post-Chemotherapy Cardiomyopathy","year":2022,"lang":"en","type":"review","venue":"Cancers","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Cardiotoxicity; Triple-negative breast cancer; Breast cancer; Cardiomyopathy; Oncology; Internal medicine; Cancer; Heart failure; Metastasis; Cancer research; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054404,0.0002691579,0.0004911689,0.0005124232,0.0002688127,0.001281483,0.0002896214,0.0009381848,0.002550093],"category_scores_gemma":[0.0004216862,0.0001062041,0.0004012136,0.0003568538,0.0005942507,0.001034946,0.0005714619,0.002632823,0.0007156886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003925758,"about_ca_system_score_gemma":0.0006215703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002231579,"about_ca_topic_score_gemma":0.0005763873,"domain_scores_codex":[0.9997913,0.00005983328,0.00001595365,0.00003157663,0.00006792141,0.00003336531],"domain_scores_gemma":[0.9997466,0.00008516435,0.00003673312,0.00001068036,0.00006886375,0.00005193704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008178526,0.0003228385,0.002047318,0.008516192,0.0001863449,0.001548298,0.0005769847,0.000722098,0.1266006,0.04004698,0.05959793,0.7590165],"study_design_scores_gemma":[0.0001169249,0.001538166,0.005464344,0.002315135,0.0002031995,0.004148121,0.0004679389,0.0006551528,0.02189581,0.01494505,0.9481939,0.00005614456],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006705848,0.970826,0.001927773,0.01201515,0.00269019,0.00002191585,0.00005912857,0.00006515765,0.005688905],"genre_scores_gemma":[0.05538601,0.920628,0.00256441,0.009417048,0.004896872,0.00005355746,0.0001423421,0.00002898985,0.006882761],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002550093,"threshold_uncertainty_score":0.008530915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05719545294662759,"score_gpt":0.377610469379163,"score_spread":0.3204150164325354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}