{"id":"W4220838371","doi":"10.1002/jlb.4hi1221-722r","title":"Transfusable neutrophil progenitors as cellular therapy for the prevention of invasive fungal infections","year":2022,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"Progenitor cell; Neutropenia; Bone marrow; Homing (biology); Progenitor; In vivo; Sepsis; Cell therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002075931,0.0001816466,0.0002155082,0.000164375,0.00007736676,0.0002664802,0.0002061805,0.000162375,0.0004965386],"category_scores_gemma":[0.0001058921,0.00005140088,0.00007657376,0.0001068094,0.0001596013,0.0001346852,0.0002458177,0.0005645962,0.0001026814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008971082,"about_ca_system_score_gemma":0.0001624451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009186249,"about_ca_topic_score_gemma":0.0002514194,"domain_scores_codex":[0.9999362,0.00002243111,0.00000468102,0.000008391402,0.00001871885,0.000009585065],"domain_scores_gemma":[0.9999658,0.000006845872,0.000008344868,0.000004672007,0.00000382104,0.00001054193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001489816,0.0005542134,0.0008461071,0.0002852903,0.00002501916,0.0002872316,0.0001260412,0.0008844679,0.8822373,0.00181239,0.0005592688,0.1108929],"study_design_scores_gemma":[0.0006558312,0.01419508,0.008867027,0.0001717557,0.0001595851,0.002026272,0.000102893,0.003572076,0.9159746,0.001083483,0.05317124,0.00002032414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9624712,0.02623371,0.008837524,0.0003220367,0.0001198278,0.0001842878,0.0001829762,0.0001275687,0.001520771],"genre_scores_gemma":[0.9816698,0.01146082,0.005189203,0.0001186681,0.00004139047,0.0001012047,0.0001997593,0.00001018119,0.00120892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004965386,"threshold_uncertainty_score":0.001661062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02490864113967155,"score_gpt":0.2697881515646986,"score_spread":0.244879510425027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}