{"id":"W4220842306","doi":"10.1111/micc.12756","title":"Defining a role of <scp>NADPH</scp> oxidase in myogenic tone development","year":2022,"lang":"en","type":"article","venue":"Microcirculation","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Western University; University of Calgary","keywords":"NOX1; NADPH oxidase; Myogenic contraction; Colocalization; Chemistry; Electrical impedance myography; Cell biology; Gq alpha subunit; Reactive oxygen species; Vascular smooth muscle; G protein-coupled receptor; Superoxide; Vasodilation; Receptor; Biochemistry; Biology; Endocrinology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002277539,0.0002415665,0.0001016175,0.0001581027,0.0001484507,0.0003063178,0.0001643067,0.0002130222,0.0006983761],"category_scores_gemma":[0.0001532682,0.00007872459,0.0001389595,0.00007154655,0.0003083622,0.0002312263,0.0002137279,0.0003659459,0.0001007738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002682671,"about_ca_system_score_gemma":0.0002343779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005689128,"about_ca_topic_score_gemma":0.0007821394,"domain_scores_codex":[0.9999055,0.00001487378,0.000005829746,0.00002837797,0.00002321498,0.00002218718],"domain_scores_gemma":[0.9998749,0.00001614644,0.00003871247,0.0000101149,0.00002717857,0.00003290879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006158421,0.00001303977,0.0007803415,0.0000313281,0.000003100211,0.00007141856,0.00001363382,0.0000353096,0.9970523,0.0004737946,0.00002404759,0.001440112],"study_design_scores_gemma":[0.0000155368,0.0004991975,0.04317212,0.00003435673,0.0000319319,0.000474139,0.0001402295,0.002620631,0.9476652,0.0008051715,0.004533833,0.000007544359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9757268,0.003408693,0.01738024,0.0003641418,0.00005324234,0.00004427055,0.0001920698,0.00005267165,0.00277786],"genre_scores_gemma":[0.9944544,0.0007822186,0.003260595,0.00005590888,0.00002117537,0.00002323824,0.00008083622,0.000005930084,0.001315663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006983761,"threshold_uncertainty_score":0.002336323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008131982698625712,"score_gpt":0.2468740650975628,"score_spread":0.2387420823989371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}