{"id":"W4220850105","doi":"10.1016/j.joca.2022.02.483","title":"ELUCIDATING DISEASE-MODIFYING MECHANISMS OF DELTA-9-TETRAHYDROCANNABINOL IN PRE-CLINICAL OSTEOARTHRITIS","year":2022,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Pharmacology and Obesity Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Public Health; Toronto Western Hospital; Ontario Medical Association; Krembil Foundation; Arthritis Society","funders":"Shaanxi University of Chinese Medicine","keywords":"Osteoarthritis; Delta-9-tetrahydrocannabinol; Disease; Medicine; Bioinformatics; Internal medicine; Biology; Pathology; Cannabinoid; Alternative medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002189584,0.0002313143,0.0003681591,0.0003273152,0.0001521093,0.0003892146,0.0002745497,0.0003500194,0.001411568],"category_scores_gemma":[0.0002166483,0.0001460942,0.0002246429,0.0001522322,0.0003244034,0.0002688366,0.0001778687,0.0006887708,0.0001943853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003175027,"about_ca_system_score_gemma":0.0005790485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00218249,"about_ca_topic_score_gemma":0.005646511,"domain_scores_codex":[0.9999381,0.00001524708,0.000006144799,0.000008024753,0.00001120257,0.00002122499],"domain_scores_gemma":[0.9999231,0.00001483936,0.00002127345,0.000005875606,0.00001969921,0.00001530817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00751172,0.001132441,0.01012872,0.001090918,0.0002982994,0.0008105086,0.0002118486,0.0004100087,0.78859,0.002906448,0.0007260044,0.1861832],"study_design_scores_gemma":[0.002447935,0.01452851,0.3534473,0.00073309,0.001731731,0.003778832,0.002032363,0.00456362,0.5565948,0.01256419,0.04744665,0.0001309037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8974921,0.09351838,0.003037371,0.001546318,0.0001709702,0.0001187458,0.0002503996,0.00003511359,0.003830615],"genre_scores_gemma":[0.9647445,0.0302178,0.001817729,0.0003729112,0.00007519629,0.00004866144,0.0001298837,0.000005686867,0.00258749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00218249,"threshold_uncertainty_score":0.004722118,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01830975012821551,"score_gpt":0.3000969377274393,"score_spread":0.2817871875992238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}