{"id":"W4220851987","doi":"10.1158/1538-7445.sabcs21-ot2-03-01","title":"Abstract OT2-03-01: RNA disruption assay (RDA) - Breast cancer response evaluation for individualized therapy (brevity/brevity-02)","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Breast cancer; Oncology; Chemotherapy; Neoadjuvant therapy; Internal medicine; Stage (stratigraphy); Clinical trial; Cancer; Biopsy; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01201827,0.0007306496,0.001074262,0.0008866658,0.0003673228,0.001732033,0.0006360427,0.0008587271,0.009334687],"category_scores_gemma":[0.008928743,0.0003892213,0.0006384815,0.0006830853,0.0006156646,0.0005695943,0.0006770684,0.0009389427,0.002638926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006151622,"about_ca_system_score_gemma":0.0008519759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003569073,"about_ca_topic_score_gemma":0.0005547809,"domain_scores_codex":[0.9941218,0.003514279,0.0005587949,0.0004987889,0.001099445,0.0002069372],"domain_scores_gemma":[0.9931063,0.002231898,0.002074594,0.001123434,0.001101827,0.000361954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.09688762,0.004089961,0.0860514,0.002379561,0.0004999901,0.0005653765,0.0005584244,0.002843721,0.2982945,0.003311174,0.04124258,0.4632757],"study_design_scores_gemma":[0.01262491,0.1138783,0.3011984,0.0008328581,0.0009654028,0.005146903,0.0003183704,0.02300104,0.3853548,0.003302154,0.1530353,0.0003414456],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.771309,0.01522561,0.1070507,0.003162395,0.001915363,0.02139462,0.02538357,0.005088996,0.04946978],"genre_scores_gemma":[0.8411772,0.001550733,0.1059316,0.002162805,0.0006363514,0.01294935,0.01339781,0.0007113339,0.02148272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01201827,"threshold_uncertainty_score":0.06355941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1193519736756182,"score_gpt":0.4604645255189903,"score_spread":0.3411125518433721,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}