{"id":"W4220853882","doi":"10.1136/rmdopen-2021-002049","title":"Effect of upadacitinib on reducing pain in patients with active psoriatic arthritis or ankylosing spondylitis: post hoc analysis of three randomised clinical trials","year":2022,"lang":"en","type":"article","venue":"RMD Open","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Chugai Pharmaceutical; Genentech; Teva Pharmaceutical Industries; Gilead Sciences; AbbVie; Sanofi; Amgen; Pfizer; Celgene; AstraZeneca; Eli Lilly and Company; UCB Pharma; Sun Pharma; GlaxoSmithKline","keywords":"Medicine; Ankylosing spondylitis; Adalimumab; Placebo; Psoriatic arthritis; Internal medicine; Post-hoc analysis; Arthritis; Rheumatoid arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01886255,0.003179847,0.01005841,0.0008619694,0.0005235935,0.002453713,0.001346775,0.001935509,0.007972857],"category_scores_gemma":[0.01853579,0.001006112,0.01891854,0.001047843,0.001220335,0.001811063,0.001280125,0.003143569,0.0007506111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001440456,"about_ca_system_score_gemma":0.001743497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001062564,"about_ca_topic_score_gemma":0.002309321,"domain_scores_codex":[0.9851124,0.01098405,0.001331023,0.001010355,0.0007461577,0.000816044],"domain_scores_gemma":[0.9827162,0.01088408,0.003119869,0.001326361,0.001104293,0.0008491557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.9600123,0.0006475131,0.0006173892,0.002087331,0.02979656,0.00003187274,0.00003681765,0.0006727795,0.0007444625,0.00004529512,0.0003799055,0.004927735],"study_design_scores_gemma":[0.8660241,0.06373676,0.007735917,0.0003002048,0.05769574,0.00007273628,0.00009375353,0.001636858,0.001086534,0.0003227229,0.001210961,0.00008364616],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9331931,0.03664019,0.004388809,0.001079997,0.002024847,0.0140521,0.004605612,0.00035158,0.00366376],"genre_scores_gemma":[0.9801267,0.005185737,0.002567379,0.0006427241,0.0003570754,0.007551822,0.001493996,0.00007922438,0.001995431],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01886255,"threshold_uncertainty_score":0.09975588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04715410151251246,"score_gpt":0.3831446492062632,"score_spread":0.3359905476937507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}