{"id":"W4220854577","doi":"10.1126/sciimmunol.abi4613","title":"Transforming growth factor–β1 in regulatory T cell biology","year":2022,"lang":"en","type":"review","venue":"Science Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":232,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; Pelotonia; Cancer Research Society; Ohio State University","keywords":"Transforming growth factor; Biology; Cytokine; Cell biology; Context (archaeology); Immunology; Regulatory T cell; Immunotherapy; T cell; Transforming growth factor beta; Cancer research; IL-2 receptor; Immune system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.001483509,0.001115834,0.003200843,0.002830862,0.001092037,0.00004403919,0.00401994,0.001909593,0.005217549],"category_scores_gemma":[0.0002377518,0.0009782816,0.0007316778,0.002699764,0.005543168,0.0003707678,0.001232614,0.003621357,0.001738908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009665081,"about_ca_system_score_gemma":0.002511396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005114053,"about_ca_topic_score_gemma":0.00004640795,"domain_scores_codex":[0.9920453,0.001439602,0.001759258,0.002095809,0.000134188,0.002525788],"domain_scores_gemma":[0.9967689,0.0007860044,0.0008139526,0.001469887,0.00009760619,0.00006365641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004340717,0.0003624913,0.00003408308,0.0008833873,0.0001944364,0.00005006512,0.0005836248,3.819103e-7,0.3473067,0.002953832,0.00009458476,0.647493],"study_design_scores_gemma":[0.001044276,0.0005166632,0.00001453381,0.0003849677,0.0001548464,0.0004863226,0.0003041601,2.223104e-7,0.01263644,0.0003401386,0.9831207,0.0009967613],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004788052,0.9807056,0.00001026706,0.00004889899,0.006599522,0.00116331,0.0001091784,0.000214203,0.006360951],"genre_scores_gemma":[0.01323589,0.983484,0.00003400407,0.00008953675,0.00004777947,0.0003995935,0.0003580662,0.00009969474,0.002251423],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9830261,"threshold_uncertainty_score":0.9993861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03132029268021047,"score_gpt":0.2797975890020957,"score_spread":0.2484772963218852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}