{"id":"W4220875542","doi":"10.1016/j.ymgme.2022.01.095","title":"EFFECT OF CREATINE SUPPLEMENTATION ON AGAT EXPRESSION AND METABOLIC INTERMEDIATES IN GAMT-DEFICIENT MICE","year":2022,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"Muscle metabolism and nutrition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"Creatine; Chemistry; Creatine Monohydrate; Internal medicine; Endocrinology; Biochemistry; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005328432,0.001654138,0.001330941,0.001361062,0.0005197907,0.0008546419,0.001137197,0.002074335,0.00332544],"category_scores_gemma":[0.000701429,0.0007207999,0.0008516427,0.0005175128,0.001690654,0.0008153975,0.0007264062,0.002627985,0.0008256442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008083954,"about_ca_system_score_gemma":0.0007594216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002281305,"about_ca_topic_score_gemma":0.002921857,"domain_scores_codex":[0.999137,0.0001648741,0.0001198029,0.0002602128,0.0001016977,0.0002163629],"domain_scores_gemma":[0.9979792,0.0002660706,0.0006408906,0.0001495175,0.0001351587,0.0008292182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01407296,0.0005003671,0.0003275895,0.00009565902,0.00004355012,0.000295393,0.00006379282,0.0001778034,0.9824127,0.000192899,0.0001254705,0.0016918],"study_design_scores_gemma":[0.0009529478,0.00375923,0.004009643,0.00006028648,0.0002310449,0.0003332927,0.0001521441,0.00159436,0.9862758,0.0002484711,0.00233007,0.00005285299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930475,0.001495554,0.001526255,0.0006312141,0.0001519382,0.0001027449,0.001648171,0.0004010049,0.0009957012],"genre_scores_gemma":[0.9843672,0.0009311622,0.004125375,0.0003326392,0.00006651432,0.0002556655,0.001322708,0.0002698909,0.0083287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00332544,"threshold_uncertainty_score":0.01112467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003563823897696816,"score_gpt":0.241117594900651,"score_spread":0.2375537710029542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}