{"id":"W4220889393","doi":"10.1038/s41598-022-09198-6","title":"Characterization of an engineered mucus microenvironment for in vitro modeling of host–microbe interactions","year":2022,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Research Nova Scotia; Dalhousie University; Natural Sciences and Engineering Research Council of Canada; Dalhousie Medical Research Foundation; Beatrice Hunter Cancer Research Institute","keywords":"Mucus; Self-healing hydrogels; Mucin; Microbiology; In vitro; Chemistry; Bacteria; Biofilm; Cell biology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002296247,0.0003196037,0.0001206641,0.0001233238,0.0001119886,0.0002616589,0.0001984355,0.0003435095,0.0003019667],"category_scores_gemma":[0.0001759959,0.0001398671,0.0001670612,0.00008950182,0.000123272,0.0001763554,0.0001492846,0.0002211959,0.00009959345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001872735,"about_ca_system_score_gemma":0.0001581805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006131457,"about_ca_topic_score_gemma":0.001031735,"domain_scores_codex":[0.9999279,0.00001053331,0.000006846082,0.00001263654,0.00002746551,0.00001474632],"domain_scores_gemma":[0.9998636,0.00003519054,0.00004116118,0.00001432769,0.00002383504,0.00002182765],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000005115585,0.000006100835,0.00007051107,0.00001171269,6.81249e-7,0.00002386852,0.000006718002,0.0006527651,0.9989774,0.00002511844,0.00000363033,0.0002163628],"study_design_scores_gemma":[0.000005005585,0.0001277282,0.001213211,0.000007014393,0.000005903332,0.00006194902,0.00002074868,0.01617063,0.9816331,0.00002504449,0.0007235626,0.000006232635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9740235,0.0005666647,0.02431759,0.00003454301,0.00002361366,0.00005558929,0.0002205323,0.0000568159,0.0007012299],"genre_scores_gemma":[0.9758137,0.0004149698,0.02292796,0.00001625074,0.000004013281,0.00006028923,0.0001688662,0.00001674222,0.000577183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006131457,"threshold_uncertainty_score":0.001358807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01519404925623036,"score_gpt":0.2072127257398029,"score_spread":0.1920186764835725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}