{"id":"W4220889692","doi":"10.1128/mbio.03088-21","title":"Evolutionary Sweeps of Subviral Parasites and Their Phage Host Bring Unique Parasite Variants and Disappearance of a Phage CRISPR-Cas System","year":2022,"lang":"en","type":"article","venue":"mBio","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"International Centre for Diarrhoeal Disease Research, Bangladesh; National Institute of Allergy and Infectious Diseases; Global Affairs Canada; Department for International Development; National Institutes of Health; Department for International Development, UK Government; Styrelsen för Internationellt Utvecklingssamarbete; Burroughs Wellcome Fund","keywords":"Vibrio cholerae; CRISPR; Biology; Cholera; El Tor; Lineage (genetic); Population; Bacteriophage; Genome; Virology; Evolutionary biology; Host (biology); Genetics; Gene; Bacteria; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002123941,0.0001278175,0.0002243144,0.0000425039,0.0001360363,0.00001167483,0.0001253327,0.00004231029,0.000006219808],"category_scores_gemma":[0.00003712092,0.000118023,0.00004471099,0.00009097684,0.0001881919,0.000007729112,0.000439034,0.00008327423,4.504146e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002069823,"about_ca_system_score_gemma":0.00003427779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001308489,"about_ca_topic_score_gemma":0.00001774736,"domain_scores_codex":[0.9990757,0.0001471986,0.0001923193,0.000271263,0.0001138179,0.0001997301],"domain_scores_gemma":[0.9995664,0.00002139489,0.00009945779,0.0002173558,0.00004762492,0.00004775206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001399999,0.00005197548,0.06377453,0.0002582303,0.000106151,0.000009973614,0.0002929889,0.000006394772,0.9349159,0.0001218784,0.00008653404,0.0002354568],"study_design_scores_gemma":[0.0008997609,0.000526789,0.5566638,0.00007992851,0.00002217611,0.00007574119,0.00103328,0.000295718,0.4394608,0.00002714164,0.0007141987,0.0002006509],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924553,0.006427392,0.0003083367,0.00005035532,0.00004085546,0.0002121859,0.0003067687,0.000008572947,0.0001902404],"genre_scores_gemma":[0.9993238,0.0003011214,0.0001326531,0.00001405755,0.00003404216,0.00002799842,0.00004492268,0.00001355306,0.0001078801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4954551,"threshold_uncertainty_score":0.4812836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007294677881119251,"score_gpt":0.2412434219264248,"score_spread":0.2339487440453055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}