{"id":"W4220889692","doi":"10.1128/mbio.03088-21","title":"Evolutionary Sweeps of Subviral Parasites and Their Phage Host Bring Unique Parasite Variants and Disappearance of a Phage CRISPR-Cas System","year":2022,"lang":"en","type":"article","venue":"mBio","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"International Centre for Diarrhoeal Disease Research, Bangladesh; National Institute of Allergy and Infectious Diseases; Global Affairs Canada; Department for International Development; National Institutes of Health; Department for International Development, UK Government; Styrelsen för Internationellt Utvecklingssamarbete; Burroughs Wellcome Fund","keywords":"Vibrio cholerae; CRISPR; Biology; Cholera; El Tor; Lineage (genetic); Population; Bacteriophage; Genome; Virology; Evolutionary biology; Host (biology); Genetics; Gene; Bacteria; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002738245,0.0001982768,0.0002635186,0.0004654899,0.0004098182,0.0009100444,0.0002557332,0.0004891465,0.00166887],"category_scores_gemma":[0.0007370906,0.0001960798,0.0003042464,0.0002945115,0.0004859857,0.0004944364,0.0007464852,0.0009855353,0.0004373142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004604619,"about_ca_system_score_gemma":0.000313699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001089066,"about_ca_topic_score_gemma":0.002167475,"domain_scores_codex":[0.9997627,0.00002159183,0.00001285604,0.00008061098,0.00007035959,0.00005193714],"domain_scores_gemma":[0.9996583,0.00008573384,0.00009001562,0.00005444826,0.00004206537,0.00006940806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001586999,0.00003062673,0.01290354,0.0001242306,0.00003592141,0.0006183237,0.0005251959,0.0004257279,0.957939,0.00228347,0.0004942716,0.02446089],"study_design_scores_gemma":[0.00003768522,0.0009670736,0.1844991,0.0001342886,0.000164664,0.00950217,0.002517121,0.008931678,0.7010144,0.004653338,0.08741699,0.0001614585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9780516,0.002242287,0.01203672,0.0006116872,0.0001235578,0.00002705682,0.0005556318,0.0003144496,0.006036929],"genre_scores_gemma":[0.9885515,0.0009027271,0.006024928,0.0003322332,0.00001954706,0.00001721617,0.0004921869,0.00005770746,0.003601892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00166887,"threshold_uncertainty_score":0.005582929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007294677881119251,"score_gpt":0.2412434219264248,"score_spread":0.2339487440453055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}