{"id":"W4220891053","doi":"10.3390/biology11030403","title":"Androgen Glucuronidation in Mice: When, Where, and How","year":2022,"lang":"en","type":"article","venue":"Biology","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier universitaire de Québec; Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Glucuronidation; Biology; Dihydrotestosterone; Androgen; Internal medicine; Sulfotransferase; Androsterone; Endocrinology; Testosterone (patch); Hydroxysteroid; Enzyme; Glucuronosyltransferase; Kidney; Microsome; Hormone; Biochemistry; Dehydrogenase; Steroid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006416378,0.000133485,0.0001916554,0.0001367697,0.0002031178,0.000009580401,0.0001869872,0.0001359317,0.001590378],"category_scores_gemma":[0.00002555384,0.0001386163,0.00003305826,0.0001349537,0.0001131313,0.00004048809,0.0002439592,0.0004869759,0.00001810105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000391724,"about_ca_system_score_gemma":0.00004982652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002820792,"about_ca_topic_score_gemma":0.00003403916,"domain_scores_codex":[0.9984108,0.0007471071,0.0001532249,0.0003004766,0.00005595394,0.0003324052],"domain_scores_gemma":[0.9995761,0.0001254563,0.00008032571,0.0000916862,0.00002175425,0.000104664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004760262,0.0004232129,0.1555004,0.00003950209,0.0001466506,0.00006389391,0.001693216,0.0002843481,0.6529242,0.0113052,0.02043202,0.1567114],"study_design_scores_gemma":[0.001794414,0.0001022874,0.002703618,8.556102e-7,0.0000370908,0.00003908341,0.0001387699,0.001506544,0.01206983,0.002721552,0.9787072,0.0001787703],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.976782,0.01536952,0.00002959846,0.004472086,0.00124365,0.0002677637,0.0001262748,0.00003374724,0.001675387],"genre_scores_gemma":[0.995011,0.001768386,0.0001229655,0.002112153,0.0001558886,0.0001134737,0.00006304683,0.00001383268,0.0006392559],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9582752,"threshold_uncertainty_score":0.9993223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08825635063079168,"score_gpt":0.4076224078820755,"score_spread":0.3193660572512838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}