{"id":"W4220899923","doi":"10.3389/fimmu.2022.818538","title":"Myeloid Responses to Extracellular Vesicles in Health and Disease","year":2022,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Cancer Institute; National Institutes of Health; Terry Fox Research Institute; Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"Extracellular; Cell biology; Extracellular vesicle; Inflammation; Extracellular vesicles; Microvesicles; Immune system; Vesicle; Biology; Innate immune system; Myeloid; Immunology; Chemistry; Biochemistry; microRNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004549545,0.0006418124,0.0008754869,0.001434806,0.0002355045,0.0009874409,0.0005315978,0.001148382,0.002932288],"category_scores_gemma":[0.0005314549,0.0001848087,0.0003033399,0.001227748,0.0004147737,0.001189794,0.000802698,0.001420726,0.001948668],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006234177,"about_ca_system_score_gemma":0.0007954377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005071014,"about_ca_topic_score_gemma":0.0008638971,"domain_scores_codex":[0.9998647,0.00002582019,0.00001757549,0.00002273475,0.00005147838,0.0000176892],"domain_scores_gemma":[0.9998222,0.00007877454,0.00002270393,0.000005282958,0.00004809071,0.0000230884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008788667,0.00003989866,0.0001592527,0.01277895,0.00005842356,0.0002275662,0.0000729368,0.0003596456,0.00319674,0.009343456,0.03845103,0.9352242],"study_design_scores_gemma":[0.000007115936,0.00005177944,0.0004240355,0.002108109,0.00003335441,0.0008502025,0.00003874208,0.00005407144,0.0005737628,0.002365917,0.9934815,0.00001149806],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001055517,0.9983178,0.0001111743,0.0003508244,0.0002495495,0.000003241076,0.00001625053,0.000007004692,0.0008385411],"genre_scores_gemma":[0.000615937,0.9983112,0.0001000091,0.0001961653,0.0001707401,0.000004975182,0.00002604354,0.000001382308,0.0005735368],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002932288,"threshold_uncertainty_score":0.009809434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01962975252933245,"score_gpt":0.2914364401072474,"score_spread":0.2718066875779149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}