{"id":"W4220910661","doi":"10.1128/spectrum.02303-21","title":"The Type IV Pilus of Plasmid TP114 Displays Adhesins Conferring Conjugation Specificity and Is Important for DNA Transfer in the Mouse Gut Microbiota","year":2022,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Université de Sherbrooke; Fonds de recherche du Québec; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Plasmid; Pilus; Horizontal gene transfer; Biology; Bacterial adhesin; Gene; Bacterial genetics; Genetics; Bacteria; Microbiology; DNA; Gut flora; Gene transfer; Bacterial conjugation; Antibiotic resistance; Escherichia coli; Genome; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007145159,0.0001903227,0.0003558015,0.0001181102,0.0003887423,0.00002369326,0.0002686396,0.0001019472,0.0001826238],"category_scores_gemma":[0.0000596417,0.0001266279,0.0001173543,0.000272467,0.0003379075,0.00002063702,0.0001027653,0.0004748063,0.00000485387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001430195,"about_ca_system_score_gemma":0.0001615081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001704,"about_ca_topic_score_gemma":0.0004797594,"domain_scores_codex":[0.9984118,0.0001496371,0.0004878229,0.0003681953,0.0001089856,0.000473543],"domain_scores_gemma":[0.9990955,0.0003462133,0.00007837169,0.0003750258,0.00005679701,0.00004812078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00138317,0.0001903932,0.004166504,0.00005108404,0.00007520018,0.00001547198,0.0008601908,0.000002556298,0.9887255,0.001250258,0.003215161,0.00006454179],"study_design_scores_gemma":[0.00288633,0.001517682,0.005270517,0.00002021461,0.00008836071,0.0004066621,0.001998657,0.00020629,0.9206361,0.00009625832,0.06666202,0.0002109027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889298,0.0008074688,0.00001418461,0.008202149,0.0001373124,0.001093191,0.0006010329,0.00001431293,0.000200535],"genre_scores_gemma":[0.9983082,0.0004011318,0.00001492228,0.0004414999,0.00007012693,0.00005336018,0.0001988858,0.00002368823,0.000488224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06808937,"threshold_uncertainty_score":0.5163736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02246866431287008,"score_gpt":0.2705042092535762,"score_spread":0.2480355449407061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}