{"id":"W4220915836","doi":"10.1016/j.ijrobp.2022.03.020","title":"Graded Prognostic Assessment (GPA) for Patients With Lung Cancer and Brain Metastases: Initial Report of the Small Cell Lung Cancer GPA and Update of the Non-Small Cell Lung Cancer GPA Including the Effect of Programmed Death Ligand 1 and Other Prognostic Factors","year":2022,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre; Centre Hospitalier de l’Université de Montréal","funders":"National Cancer Institute; National Institutes of Health; National Center for Advancing Translational Sciences; University of Minnesota","keywords":"Medicine; Lung cancer; Internal medicine; Adenocarcinoma; Oncology; Anaplastic lymphoma kinase; Brain metastasis; Lung; Epidermal growth factor receptor; Cancer; Population; Metastasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001036817,0.0002502109,0.0006346543,0.0001098893,0.0002414376,0.00002176651,0.0003255342,0.00007667772,0.000009349596],"category_scores_gemma":[0.0004161192,0.0001309778,0.0001488979,0.0002207963,0.0004160699,0.00009306971,0.0003335169,0.0004981133,6.453966e-9],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006565254,"about_ca_system_score_gemma":0.001169798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004734306,"about_ca_topic_score_gemma":0.0001471945,"domain_scores_codex":[0.9977586,0.0004560641,0.0007080615,0.000283319,0.0005244138,0.0002695758],"domain_scores_gemma":[0.9955432,0.001562843,0.001959174,0.0001648095,0.0006905168,0.00007949048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007019104,0.0002566753,0.9905993,0.0004329145,0.001597192,0.000006458278,0.001430391,0.0005440446,0.001458162,0.00005722087,0.0002509656,0.002664754],"study_design_scores_gemma":[0.01600754,0.003784769,0.951289,0.0007149526,0.003072003,0.0000549195,0.000391222,0.004826349,0.01799244,0.0001561564,0.001439928,0.0002706889],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910586,0.002251925,0.0003350185,0.001950312,0.0006242787,0.003012019,0.0007430859,0.000005944718,0.00001881435],"genre_scores_gemma":[0.9981769,0.0003804573,0.0002795006,0.0002265884,0.0002408645,0.0006075348,0.00003700376,0.00003328119,0.00001790079],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03931029,"threshold_uncertainty_score":0.5341118,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02320506572987794,"score_gpt":0.3732619163356526,"score_spread":0.3500568506057747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}