{"id":"W4220941991","doi":"10.1002/dta.3249","title":"Detection of insulin analogues and large peptides >2 kDa in urine","year":2022,"lang":"en","type":"article","venue":"Drug Testing and Analysis","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"World Anti-Doping Agency","keywords":"Chromatography; Detection limit; Chemistry; Urine; Insulin; Solid phase extraction; Extraction (chemistry); Peptide; Ion suppression in liquid chromatography–mass spectrometry; Elution; Tandem mass spectrometry; Mass spectrometry; Biochemistry; Endocrinology; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007340166,0.0008535685,0.0003693556,0.001269918,0.000260925,0.0006157265,0.0004760637,0.0009027674,0.0008563249],"category_scores_gemma":[0.001055664,0.0003145252,0.000289633,0.0005351433,0.0003769066,0.0004127137,0.0003151727,0.0005110148,0.0005360265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002334564,"about_ca_system_score_gemma":0.0003523714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005525018,"about_ca_topic_score_gemma":0.0008658696,"domain_scores_codex":[0.9989384,0.0002153915,0.00006896753,0.0002938199,0.0004161512,0.00006721306],"domain_scores_gemma":[0.9993437,0.0002478242,0.0001599455,0.00003670459,0.0001341101,0.00007767768],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007668211,0.00004073531,0.001362228,0.00008551498,0.00001343841,0.0001163852,0.0000250052,0.00006825642,0.9907811,0.00003923702,0.00007987087,0.00731159],"study_design_scores_gemma":[0.00001777368,0.0006283199,0.01532703,0.00005400057,0.00003819224,0.001809767,0.00007343412,0.002315459,0.9767281,0.0001148061,0.002865063,0.00002796462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8459367,0.0119457,0.1345203,0.0003254882,0.0002913749,0.0003477754,0.001254586,0.00147285,0.003905415],"genre_scores_gemma":[0.7860855,0.007717108,0.1965665,0.0006121645,0.00009714702,0.0003539431,0.001494639,0.0001354508,0.006937506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001269918,"threshold_uncertainty_score":0.003881872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01163322297412958,"score_gpt":0.2515062152642365,"score_spread":0.2398729922901069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}