{"id":"W4220955147","doi":"10.3390/ijms23063259","title":"Microbe-Immune Crosstalk: Evidence That T Cells Influence the Development of the Brain Metabolome","year":2022,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Joseph’s Healthcare Hamilton; St. Michael's Hospital; McMaster University","funders":"NIHR Imperial Biomedical Research Centre; Biotechnology and Biological Sciences Research Council; McMaster University; Ontario Brain Institute; Medical Research Council; National Institute for Health and Care Research","keywords":"Metabolome; Immune system; Crosstalk; Biology; Computational biology; Neuroscience; Cell biology; Metabolomics; Immunology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002947179,0.0003806496,0.0003137382,0.0004746436,0.000185549,0.0006067062,0.0001870989,0.0004406098,0.001787919],"category_scores_gemma":[0.000353363,0.0001378931,0.0002400271,0.0001999357,0.0004727023,0.0004041731,0.0005056592,0.0005532939,0.0002899034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002778116,"about_ca_system_score_gemma":0.0003438511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005835259,"about_ca_topic_score_gemma":0.00118249,"domain_scores_codex":[0.9998059,0.00004003895,0.00001029111,0.00004850224,0.00003854969,0.00005681573],"domain_scores_gemma":[0.9998079,0.00003267168,0.00005308916,0.0000134368,0.00002856267,0.00006436193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001217029,0.00009649455,0.01063189,0.0002956777,0.00009728467,0.0008376699,0.0001671089,0.0001165552,0.9653443,0.0005438039,0.0003980748,0.02025417],"study_design_scores_gemma":[0.0001273099,0.0023111,0.3896907,0.0002107565,0.0003745814,0.002835027,0.001020055,0.001002478,0.5865209,0.002758782,0.01308561,0.00006266692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9745269,0.0172825,0.002938091,0.000892089,0.0001333072,0.00003235445,0.0006085918,0.00006406401,0.003522105],"genre_scores_gemma":[0.983482,0.01173865,0.001954655,0.0003632394,0.00006712426,0.00004562328,0.0002792564,0.00002311674,0.002046266],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001787919,"threshold_uncertainty_score":0.005981207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03350897464022835,"score_gpt":0.296743746511001,"score_spread":0.2632347718707727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}