{"id":"W4220976926","doi":"10.1128/iai.00565-21","title":"Characterization of the Phase-Variable Autotransporter Lav Reveals a Role in Host Cell Adherence and Biofilm Formation in Nontypeable Haemophilus influenzae","year":2022,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Health and Medical Research Council; National Institute on Deafness and Other Communication Disorders; Australian Research Council; National Institutes of Health; Medical Research Council; Children's Health Foundation","keywords":"Haemophilus influenzae; Biology; Phase variation; Microbiology; Haemophilus; Pasteurellaceae; Gene; Biofilm; Locus (genetics); Phenotype; Bacteria; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001007965,0.00013219,0.0001202876,0.0001250938,0.0000888345,0.0002201412,0.0001319148,0.0001704555,0.0003250761],"category_scores_gemma":[0.0001754444,0.00006508258,0.0001778906,0.00009516821,0.0001321009,0.0001373512,0.0001726777,0.0002702711,0.0001724564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001706839,"about_ca_system_score_gemma":0.0001229293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001400078,"about_ca_topic_score_gemma":0.001494162,"domain_scores_codex":[0.9999348,0.00001111563,0.000004683902,0.000009072589,0.00002406787,0.00001634634],"domain_scores_gemma":[0.9998876,0.00002512143,0.0000197567,0.00001415078,0.00002893853,0.00002432235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002626646,0.000006724382,0.0003433231,0.000003781322,7.283751e-7,0.00001379993,0.00001174208,0.000008944487,0.9993846,0.00001647831,0.000003638932,0.0001799371],"study_design_scores_gemma":[0.000007368444,0.0003744691,0.05089254,0.000004650642,0.00001128595,0.0005262192,0.0001639392,0.001634126,0.9449211,0.0000692821,0.001388452,0.000006653255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991541,0.0001168571,0.0004300618,0.00001590051,0.000002537507,0.000004337077,0.0001104348,0.000003984809,0.0001618683],"genre_scores_gemma":[0.9968271,0.00011522,0.001089558,0.00002480763,0.000004787461,0.000008200921,0.0008291643,0.000008333166,0.001092801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001400078,"threshold_uncertainty_score":0.002783835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01279260570548554,"score_gpt":0.2345233366137514,"score_spread":0.2217307309082659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}