{"id":"W4220982805","doi":"10.1038/s41467-022-29189-5","title":"Genetic regulation of post-translational modification of two distinct proteins","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Global Health Research","funders":"Medical Research Council; Russian Science Foundation; Horizon 2020 Framework Programme; Research Councils UK; Hrvatska Zaklada za Znanost; European Commission","keywords":"Glycosylation; Biology; Transferrin; Gene; Genetics; Fucosylation; Computational biology; Glycoprotein; Glycan; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001499918,0.0002179655,0.000135768,0.0003181005,0.0001015399,0.0003553736,0.0001512756,0.0002531764,0.0006820029],"category_scores_gemma":[0.0002400363,0.0001000604,0.0002199735,0.0002063107,0.0002731158,0.0001328011,0.0004259581,0.0003481041,0.0001978074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002412744,"about_ca_system_score_gemma":0.0001087297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003404618,"about_ca_topic_score_gemma":0.0004573501,"domain_scores_codex":[0.9997726,0.0000459249,0.0000130044,0.00006416018,0.00005522626,0.00004917723],"domain_scores_gemma":[0.9997417,0.00005363186,0.0001017156,0.00003113476,0.00002209097,0.00004979578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001025513,0.00001069155,0.002297176,0.00001099553,0.00001115795,0.00008123066,0.00001577596,0.00004432811,0.9958525,0.0001892743,0.00001605816,0.001368225],"study_design_scores_gemma":[0.00002031144,0.0003143032,0.2614565,0.00001307584,0.00006951433,0.001230176,0.0001192142,0.002934448,0.7298226,0.0005477851,0.003453523,0.0000186059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970662,0.0004989078,0.001662649,0.0000415761,0.00001342355,0.00000452371,0.0001169715,0.00002740068,0.000568345],"genre_scores_gemma":[0.9981498,0.0001624061,0.000755381,0.00002326734,0.000004546169,0.000004830325,0.0001518776,0.00001091452,0.0007369617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006820029,"threshold_uncertainty_score":0.002281487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01829437306328808,"score_gpt":0.2892011555154796,"score_spread":0.2709067824521915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}