{"id":"W4220987608","doi":"10.1007/s13555-022-00703-3","title":"Enhanced Effectiveness of Adalimumab Compared to Topical/Traditional Systemic Agents in the Treatment of Moderate to Severe Plaque Psoriasis: Results from a Canadian Observational Epidemiologic Study (COMPLETE-PS)","year":2022,"lang":"en","type":"article","venue":"Dermatology and Therapy","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dermatrials Research; TransCanada (Canada); Memorial University of Newfoundland; Barrie Urology Group; Lynde Centre for Dermatology","funders":"AbbVie","keywords":"Plaque psoriasis; Adalimumab; Psoriasis; Observational study; Medicine; Dermatology; Internal medicine; Tumor necrosis factor alpha","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005828107,0.0003546776,0.0006046183,0.000578865,0.0009499762,0.001055404,0.0008391329,0.0004565891,0.002201205],"category_scores_gemma":[0.0116392,0.0002588195,0.001820554,0.002323802,0.0005439428,0.0002547624,0.0004183444,0.0007616915,0.0001263561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00733139,"about_ca_system_score_gemma":0.01528462,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.8434846,"about_ca_topic_score_gemma":0.8441386,"domain_scores_codex":[0.9962863,0.001118142,0.0003051765,0.0004994321,0.00146824,0.0003227573],"domain_scores_gemma":[0.9933037,0.001278058,0.002517308,0.0004101471,0.001886146,0.0006046335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009367171,0.0003476866,0.9638497,0.001165482,0.004049158,0.00004355104,0.0002531503,0.0002535055,0.0003124243,0.0001466685,0.002318097,0.01789337],"study_design_scores_gemma":[0.0008566418,0.0005056436,0.995174,0.0001246644,0.001658991,0.0000488634,0.00009730073,0.0002785471,0.00007838947,0.00002979756,0.001131556,0.00001565747],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.972737,0.01361029,0.0003792989,0.0006146092,0.00006377442,0.0003522169,0.009960891,0.00001938406,0.002262502],"genre_scores_gemma":[0.9943123,0.002252166,0.0005012938,0.0001955686,0.00003376871,0.00005832713,0.002367315,0.00000544683,0.0002738658],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1565154,"threshold_uncertainty_score":0.3148742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1149462520222208,"score_gpt":0.2949359315501205,"score_spread":0.1799896795278997,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}