{"id":"W4220991301","doi":"10.1158/1538-7445.sabcs21-gs1-01","title":"Abstract GS1-01: KEYNOTE-522 study of neoadjuvant pembrolizumab + chemotherapy vs placebo + chemotherapy, followed by adjuvant pembrolizumab vs placebo for early-stage TNBC: Event-free survival sensitivity and subgroup analyses","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Medicine; Carboplatin; Placebo; Internal medicine; Oncology; Pembrolizumab; Epirubicin; Stage (stratigraphy); Chemotherapy; Cyclophosphamide; Cisplatin; Cancer; Pathology; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007991422,0.00279349,0.004569234,0.0008142615,0.0004063575,0.001723297,0.001227723,0.002233349,0.01107233],"category_scores_gemma":[0.006131167,0.000788006,0.009646003,0.0008823205,0.0008526133,0.001177898,0.0007420736,0.003469317,0.001105583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001284246,"about_ca_system_score_gemma":0.001266193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001073018,"about_ca_topic_score_gemma":0.003172474,"domain_scores_codex":[0.9961253,0.002654852,0.0003208366,0.000388098,0.0002398736,0.0002710157],"domain_scores_gemma":[0.9977362,0.001101527,0.0004805896,0.0002977042,0.0001339274,0.0002499268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9671709,0.0006483361,0.0011374,0.00181109,0.0191262,0.00005903193,0.0000335093,0.0005911899,0.002147437,0.0001244052,0.001456117,0.005694494],"study_design_scores_gemma":[0.8981385,0.0486636,0.009377855,0.0002309957,0.03672535,0.0001098166,0.00007052823,0.001486304,0.00131606,0.0009874444,0.002823216,0.00007026345],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8991285,0.04603601,0.004208322,0.003142629,0.003075831,0.01662594,0.01808489,0.0004926119,0.009205274],"genre_scores_gemma":[0.9690076,0.004495557,0.001939933,0.002439619,0.0008847107,0.008584881,0.005655341,0.00007048145,0.006921895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01107233,"threshold_uncertainty_score":0.04226315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07198443318772366,"score_gpt":0.4048215236955636,"score_spread":0.3328370905078399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}