{"id":"W4220996375","doi":"10.1101/2022.03.28.486083","title":"GLOBAL HOST RESPONSES TO THE MICROBIOTA AT SINGLE CELL RESOLUTION IN GNOTOBIOTIC ZEBRAFISH","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institute for Advanced Research","funders":"National Institutes of Health; University of Oregon","keywords":"Biology; Zebrafish; Cell type; Immune system; Transcriptome; Cell biology; Progenitor cell; Cell; Gut flora; Gene expression; Gene; Stem cell; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008484858,0.0001718692,0.0002230154,0.000340636,0.0002165761,0.0002232352,0.0001757318,0.0002701266,0.001224349],"category_scores_gemma":[0.00008324275,0.0001833717,0.0002448598,0.0001462403,0.0003092596,0.0001671249,0.0002976212,0.0005455108,0.0003091154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006080884,"about_ca_system_score_gemma":0.0002717501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006383081,"about_ca_topic_score_gemma":0.0124562,"domain_scores_codex":[0.999925,0.000002841474,0.000004461782,0.00002599757,0.00002329457,0.00001854101],"domain_scores_gemma":[0.9999126,0.00001367929,0.00002300797,0.000007470733,0.00002059105,0.00002256515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002314541,0.000001632595,0.0005359474,0.00001374677,0.000001749888,0.00001918597,0.0000196607,0.00005843323,0.9988721,0.00004019656,0.00002469405,0.0003894906],"study_design_scores_gemma":[0.00002369556,0.0002831848,0.1862803,0.00002856246,0.00004791769,0.000240651,0.00050242,0.005497642,0.8020419,0.0004105619,0.00459885,0.00004425596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891867,0.0005389315,0.004964429,0.0001068255,0.00002216361,0.0000282059,0.003182536,0.0001081344,0.001862101],"genre_scores_gemma":[0.9847754,0.0005435357,0.00605182,0.0001842935,0.00001011049,0.00008989288,0.001936624,0.00008386085,0.006324529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006383081,"threshold_uncertainty_score":0.01269186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01213045553748494,"score_gpt":0.2261003092466766,"score_spread":0.2139698537091916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}