{"id":"W4220998771","doi":"10.1038/s41598-022-06780-w","title":"The fliR gene contributes to the virulence of S. marcescens in a Drosophila intestinal infection model","year":2022,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institutes of Health; Centre National de la Recherche Scientifique; Agencia Nacional de Promoción Científica y Tecnológica; Consejo Nacional de Investigaciones Científicas y Técnicas; Université de Strasbourg; Higher Education Commision, Pakistan; Fondation pour la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Serratia marcescens; Virulence; Microbiology; Biology; Flagellum; Bacteria; Pathogen; Intestinal epithelium; Epithelium; Escherichia coli; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.004066447,0.000103753,0.0001552943,0.0001469877,0.00130361,0.00005460336,0.0003064252,0.00004492006,0.00006337871],"category_scores_gemma":[0.0003845887,0.00006780768,0.00007015468,0.0006372107,0.0004391674,0.00004966139,0.000442143,0.000244466,0.0000350295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001116944,"about_ca_system_score_gemma":0.0002133794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003263109,"about_ca_topic_score_gemma":0.0002607406,"domain_scores_codex":[0.9982924,0.0004017774,0.0004918562,0.0003777316,0.000113702,0.0003224682],"domain_scores_gemma":[0.9987528,0.0001356779,0.0002409701,0.0007285014,0.0001300416,0.00001200633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001140598,0.0000636301,0.0005001219,0.000003108151,0.00001752237,0.00002836461,0.0004569723,0.003999973,0.9862105,0.004281998,0.003799369,0.0005243628],"study_design_scores_gemma":[0.0002501877,0.0001147866,0.001162777,0.00002531437,0.0000176318,0.0008583517,0.0002001567,0.002655688,0.9219783,0.02754878,0.04505635,0.0001316947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896562,0.0008334435,0.001021051,0.001122436,0.006516416,0.0005634273,0.000009316313,0.00002964629,0.0002480775],"genre_scores_gemma":[0.9965304,0.000005376235,0.00004407095,0.0001583635,0.000005256811,0.0001530088,0.00002533793,0.000008308274,0.003069861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06423224,"threshold_uncertainty_score":0.9999965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01233083692831202,"score_gpt":0.2314776878156053,"score_spread":0.2191468508872933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}