{"id":"W4221000688","doi":"10.1158/1538-7445.sabcs21-p3-18-04","title":"Abstract P3-18-04: Evaluating <b>de</b>-escalation of <b>b</b>reast <b>r</b>adiation (<b>DEBRA</b>) following lumpectomy for breast conservative treatment of stage 1, hr+, HER2-, RS ≤18 breast cancer: NRG-BR007 a phase III trial","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Medicine; Lumpectomy; Breast cancer; Tamoxifen; Oncology; Radiation therapy; Internal medicine; Stage (stratigraphy); Aromatase inhibitor; Breast-conserving surgery; Cancer; Mastectomy; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00111812,0.000908446,0.0008504272,0.0002451546,0.0002836977,0.0009038743,0.0007470541,0.001186235,0.01092498],"category_scores_gemma":[0.001029655,0.0002588464,0.001168904,0.0002187504,0.0005550277,0.0006137631,0.0002788191,0.003118573,0.001613597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006754961,"about_ca_system_score_gemma":0.001017573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00109907,"about_ca_topic_score_gemma":0.003072513,"domain_scores_codex":[0.9997009,0.0001606383,0.00001337494,0.00004597595,0.00002891989,0.00005016424],"domain_scores_gemma":[0.9993792,0.0001553716,0.000130819,0.00003459665,0.00004145849,0.0002586276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.840248,0.02842225,0.003121521,0.001353652,0.001303402,0.0001320149,0.0001484952,0.001219014,0.01448088,0.0006670429,0.01403274,0.09487101],"study_design_scores_gemma":[0.7879018,0.197386,0.005532653,0.0001570334,0.0004832901,0.0001421626,0.00006250542,0.001028776,0.001693302,0.000502164,0.005086401,0.00002394288],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.976761,0.004215315,0.0007673313,0.002301195,0.000437121,0.00425576,0.003288064,0.0002652864,0.007708914],"genre_scores_gemma":[0.9728732,0.002615334,0.002856281,0.003539134,0.0003625996,0.004540758,0.002784193,0.00006836972,0.01036011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01092498,"threshold_uncertainty_score":0.03654766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1248516108655303,"score_gpt":0.4729777414693486,"score_spread":0.3481261306038183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}