{"id":"W4221008288","doi":"10.5206/uwomj.v90i1.14009","title":"CRISPR: On the road to restoring sight to the blind","year":2022,"lang":"en","type":"article","venue":"University of Western Ontario Medical Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Disease; Blindness; Cas9; Medicine; Biology; Gene; Genetics; Pathology; Optometry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002130183,0.0008551674,0.0007983518,0.001102882,0.001220857,0.003683456,0.001206013,0.003001605,0.02199471],"category_scores_gemma":[0.002490035,0.0005113481,0.0003953975,0.0005693525,0.003737043,0.002021525,0.002780189,0.005500544,0.00763367],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001896277,"about_ca_system_score_gemma":0.002282074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004688464,"about_ca_topic_score_gemma":0.00536789,"domain_scores_codex":[0.9989107,0.0001818765,0.00004518082,0.0001234942,0.0005283284,0.0002104337],"domain_scores_gemma":[0.9984205,0.0003276899,0.0001200986,0.0001167804,0.0003305754,0.0006844568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005264638,0.00008672693,0.0008129682,0.0008910972,0.00006101351,0.0006149712,0.0003375363,0.0008583552,0.04791256,0.0851008,0.4286544,0.4341431],"study_design_scores_gemma":[0.00006255492,0.0001880409,0.0007675242,0.0004233036,0.00002918926,0.001299309,0.0001579207,0.0006624509,0.01812609,0.02750877,0.950714,0.00006087069],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01945911,0.305871,0.2109813,0.2314268,0.0262602,0.0004409258,0.004221203,0.02321254,0.1781269],"genre_scores_gemma":[0.2024912,0.4167972,0.1174816,0.08866376,0.01027118,0.0004187028,0.004911983,0.003088191,0.1558762],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02199471,"threshold_uncertainty_score":0.07357961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01289618859216944,"score_gpt":0.2568037429495783,"score_spread":0.2439075543574089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}