{"id":"W4221013822","doi":"10.5772/intechopen.103718","title":"Tumor-Derived Exosome and Immune Modulation","year":2022,"lang":"en","type":"book-chapter","venue":"Physiology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Microvesicles; Immunotherapy; Immune system; Exosome; Cancer immunotherapy; Biology; Tumor microenvironment; Immunosuppression; Myeloid-derived Suppressor Cell; Cancer research; Immunology; Cell biology; Endocytosis; Cancer; Cell; Suppressor; microRNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006049435,0.0002578886,0.0002681892,0.00004693624,0.00009524658,0.000007192529,0.0001909362,0.0001964663,0.000683651],"category_scores_gemma":[0.00002248106,0.0002889717,0.000128615,0.00001015808,0.000182741,0.000002524517,0.0004497121,0.0002062651,0.00002986786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001929944,"about_ca_system_score_gemma":0.00004890311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005489793,"about_ca_topic_score_gemma":0.000001737987,"domain_scores_codex":[0.9989083,0.00004378492,0.0002245104,0.0005449925,0.00008985418,0.0001884911],"domain_scores_gemma":[0.9991823,0.00001243726,0.0001777948,0.0005232191,0.00003498845,0.00006925485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000099611,0.0000185024,0.000005062301,0.00003493594,0.00008287499,0.00001186987,0.000009937366,0.00004980226,0.9900979,0.00812674,0.0003186857,0.001144093],"study_design_scores_gemma":[0.0020461,0.001213226,0.01267788,0.0000587334,0.0002616521,0.000149178,0.00002958945,0.0003202786,0.1275825,0.1110389,0.742459,0.002162991],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8194734,0.0224701,0.0001123517,0.0001945156,0.0008235464,0.0008219466,0.0002975556,0.00008083432,0.1557257],"genre_scores_gemma":[0.9393124,0.000752697,0.0001575669,0.0002992829,0.000457112,0.00004113504,0.001820256,0.00009738588,0.05706218],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8625154,"threshold_uncertainty_score":0.9999563,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009537311207965266,"score_gpt":0.2185018025316357,"score_spread":0.2089644913236705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}