{"id":"W4221022070","doi":"10.3389/fimmu.2022.765319","title":"Targeting the Retinoid X Receptor Pathway Prevents and Ameliorates Murine Chronic Graft-Versus-Host Disease","year":2022,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Panthera","keywords":"Medicine; Graft-versus-host disease; Immunology; Bronchiolitis obliterans; Hematopoietic stem cell transplantation; Minor histocompatibility antigen; Transplantation; Internal medicine; Major histocompatibility complex; Antigen","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004108762,0.0007274419,0.0005008254,0.0006434206,0.0001739009,0.0002966846,0.0003824315,0.0004789602,0.001307777],"category_scores_gemma":[0.00008420303,0.0001551057,0.0004188891,0.0001613789,0.0004758777,0.0002817062,0.0001797865,0.0009112812,0.0002758432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001661563,"about_ca_system_score_gemma":0.0003240862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002746586,"about_ca_topic_score_gemma":0.0004732569,"domain_scores_codex":[0.9997285,0.00007172344,0.00002739235,0.00003615842,0.00006087658,0.00007524699],"domain_scores_gemma":[0.9998969,0.00001222524,0.00003555313,0.00001352601,0.000009301996,0.00003253913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007427185,0.000393666,0.0001987956,0.0001412766,0.00001234518,0.00007412385,0.0000227354,0.0001427723,0.9939607,0.0001719883,0.0001012113,0.004037634],"study_design_scores_gemma":[0.0003187419,0.00732452,0.004824908,0.00002709381,0.00007013781,0.0003911025,0.00006692443,0.001241911,0.9815057,0.0001388436,0.004078072,0.00001216576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891676,0.004975654,0.003076602,0.0002551168,0.00008450603,0.00007574284,0.0003521317,0.0002572332,0.001755479],"genre_scores_gemma":[0.9884298,0.004052061,0.003596985,0.0001234511,0.00003980237,0.000124557,0.0004255752,0.00002771283,0.003179974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001307777,"threshold_uncertainty_score":0.004374981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008869405823037866,"score_gpt":0.231264739259902,"score_spread":0.2223953334368642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}