{"id":"W4221023205","doi":"10.3390/antiox11030560","title":"A Metabolic Network Mediating the Cycling of Succinate, a Product of ROS Detoxification into α-Ketoglutarate, an Antioxidant","year":2022,"lang":"en","type":"article","venue":"Antioxidants","topic":"Biochemical Acid Research Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Laurentian University","funders":"Northern Ontario Heritage Fund Corporation; Bruce Power; U.S. Department of Veterans Affairs","keywords":"Metabolic pathway; Biochemistry; Antioxidant; Enzyme; Succinate dehydrogenase; Pseudomonas fluorescens; Citric acid cycle; Chemistry; Biology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001074012,0.0001544492,0.0002707619,0.00005212291,0.0003214413,0.00001057587,0.0004903619,0.0000495609,0.00001424582],"category_scores_gemma":[0.0003874679,0.0001069602,0.0001055488,0.0004829389,0.0002241532,0.000009924417,0.0005175583,0.0001971526,9.959556e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001074186,"about_ca_system_score_gemma":0.00009468553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001158124,"about_ca_topic_score_gemma":0.00002693971,"domain_scores_codex":[0.9981409,0.0003070045,0.0004402786,0.0003968528,0.0003867577,0.0003282198],"domain_scores_gemma":[0.9988298,0.00004153263,0.0003143476,0.000541875,0.0002194179,0.00005305923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000110871,0.0001475068,0.01153344,0.00004575052,0.0001083722,9.731127e-7,0.0002364068,0.0004533262,0.98278,0.0001012188,0.0001847741,0.004297317],"study_design_scores_gemma":[0.0002885198,0.0002617499,0.03939212,0.00001301097,0.00003038581,0.000008138471,0.0003933962,0.0002374509,0.9571715,0.00019795,0.001864662,0.0001411321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934168,0.005570686,0.0001807521,0.0002279481,0.0001165427,0.0003618018,0.00003047676,0.00001155689,0.00008347289],"genre_scores_gemma":[0.997321,0.000901557,0.001290653,0.00005777929,0.0002094805,0.00008431646,0.00005492986,0.00002225363,0.00005809164],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02785868,"threshold_uncertainty_score":0.436171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01311481197140885,"score_gpt":0.2817350209938252,"score_spread":0.2686202090224163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}