{"id":"W4221041873","doi":"10.1007/s40120-022-00338-8","title":"Alzheimer’s Disease: Epidemiology and Clinical Progression","year":2022,"lang":"en","type":"review","venue":"Neurology and Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":566,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Eisai","keywords":"Dementia; Medicine; Epidemiology; Cognitive decline; Disease; Neurodegeneration; Neurology; Alzheimer's disease; Biomarker; Gerontology; Internal medicine; Psychiatry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004683829,0.0005905204,0.001441734,0.006066374,0.0004229034,0.002701956,0.0006444664,0.000822747,0.00173271],"category_scores_gemma":[0.01314824,0.0003927233,0.001309465,0.01035683,0.0006277311,0.001829343,0.0008307449,0.001535696,0.0005066002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001015399,"about_ca_system_score_gemma":0.002255706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005783834,"about_ca_topic_score_gemma":0.006322193,"domain_scores_codex":[0.9963936,0.000807123,0.001218018,0.000497775,0.0009572609,0.0001262438],"domain_scores_gemma":[0.9916191,0.002334249,0.003590952,0.0002251274,0.001947327,0.0002832394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00103525,0.0001914473,0.4808857,0.04856392,0.004243566,0.0009637567,0.0009562448,0.0006895516,0.0004168138,0.003664058,0.02888737,0.4295023],"study_design_scores_gemma":[0.0002033644,0.0005648115,0.8435974,0.03846867,0.004048997,0.009916361,0.001346937,0.0009845035,0.0002257295,0.008727834,0.09177814,0.0001373279],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02056002,0.9719192,0.0004938997,0.001351993,0.0003697873,0.0001356462,0.002338002,0.00002978708,0.00280166],"genre_scores_gemma":[0.1967813,0.7940899,0.002112986,0.0009147032,0.001379184,0.0002407012,0.003677199,0.00002131036,0.0007825808],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006066374,"threshold_uncertainty_score":0.02477074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2497319148056762,"score_gpt":0.5273113714621325,"score_spread":0.2775794566564563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}