{"id":"W4221041873","doi":"10.1007/s40120-022-00338-8","title":"Alzheimer’s Disease: Epidemiology and Clinical Progression","year":2022,"lang":"en","type":"review","venue":"Neurology and Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":566,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Eisai","keywords":"Dementia; Medicine; Epidemiology; Cognitive decline; Disease; Neurodegeneration; Neurology; Alzheimer's disease; Biomarker; Gerontology; Internal medicine; Psychiatry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001341427,0.0002543296,0.001384481,0.000126553,0.0001567,0.000006006509,0.00008901438,0.0002820204,0.0008999914],"category_scores_gemma":[0.0002545318,0.0001675299,0.0002416826,0.00009097193,0.0004808501,0.00002082358,0.0001648288,0.001109031,0.0000137074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003253063,"about_ca_system_score_gemma":0.0001761396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001589391,"about_ca_topic_score_gemma":2.057444e-7,"domain_scores_codex":[0.9961461,0.002246419,0.0004965661,0.0006387182,0.0001257347,0.0003463925],"domain_scores_gemma":[0.9975476,0.001694004,0.0001737969,0.0002449299,0.00001889688,0.0003207804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006280247,0.0002115301,0.05358667,0.0004949376,0.0003469829,0.0002084271,0.000002639044,6.19842e-10,2.104264e-8,0.00009994463,0.0003902351,0.9440306],"study_design_scores_gemma":[0.0009767269,0.003190347,0.0402226,0.0001998621,0.0008231666,0.000291979,7.094782e-7,0.000002635755,3.319071e-8,0.000267007,0.953915,0.0001099593],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001645519,0.9949421,0.000001355087,0.001477978,0.0002327146,0.001232735,0.00001160414,0.0000343669,0.0004215762],"genre_scores_gemma":[0.0001151585,0.9953244,0.00001553948,0.00376388,0.0002133005,0.0002760898,0.000124597,0.0000316259,0.0001354494],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9535248,"threshold_uncertainty_score":0.9854275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2497319148056762,"score_gpt":0.5273113714621325,"score_spread":0.2775794566564563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}