{"id":"W4221043327","doi":"10.1002/anie.202112645","title":"High‐Resolution NMR H/D Exchange of Human Superoxide Dismutase Inclusion Bodies Reveals Significant Native Features Despite Structural Heterogeneity","year":2022,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Advanced MRI Techniques and Applications","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Toronto; University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Superoxide dismutase; High resolution; Chemistry; Biochemistry; Enzyme; Geography; Remote sensing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001385415,0.0001403564,0.0000885336,0.0001170591,0.0001139001,0.000145815,0.0001035566,0.000175069,0.0003225669],"category_scores_gemma":[0.0001418624,0.00009232926,0.00006888435,0.00008372375,0.0001592411,0.0001273079,0.0001179739,0.0003152274,0.0001101582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007744404,"about_ca_system_score_gemma":0.00006343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004012838,"about_ca_topic_score_gemma":0.0003944224,"domain_scores_codex":[0.9999661,0.000007331122,0.000002329813,0.000008850522,0.00000868515,0.000006619385],"domain_scores_gemma":[0.9999285,0.00001766804,0.00001925912,0.00001024343,0.00001158116,0.00001270589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005108104,0.000004336028,0.0003550184,0.00001435834,0.000002912366,0.0000292281,0.00003037323,0.0000362785,0.9988458,0.00002387842,0.00002511288,0.0005815964],"study_design_scores_gemma":[0.00001069273,0.0001375691,0.02106975,0.000009058917,0.00001941003,0.0006335042,0.0001277937,0.001585875,0.9747173,0.0001445065,0.00153541,0.000009178928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952276,0.0004987607,0.003447617,0.00008126326,0.000006508769,0.00000411723,0.000138901,0.00005003525,0.0005453089],"genre_scores_gemma":[0.9955072,0.0003959183,0.003146144,0.00003789012,0.000003682591,0.000005695208,0.0002987386,0.00001543153,0.0005892811],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004012838,"threshold_uncertainty_score":0.001079142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02133211456751048,"score_gpt":0.3213795157524385,"score_spread":0.300047401184928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}