{"id":"W4221061856","doi":"10.3390/brainsci12030352","title":"Substance Abuse in Emerging Adults: The Role of Neuromelanin and Ventral Striatal Response to Social and Monetary Rewards","year":2022,"lang":"en","type":"article","venue":"Brain Sciences","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Ottawa Mental Health Centre; University of Ottawa","funders":"National Institute of Child Health and Human Development; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute on Drug Abuse; National Institute on Aging; National Institute of Mental Health; Temple University; Myer and Rosaline Feinstein Center for American Jewish History, Temple University","keywords":"Ventral striatum; Substantia nigra; Reward system; Psychology; Dopamine; Functional magnetic resonance imaging; Striatum; Substance abuse; Neuroscience; Neuromelanin; Ventral tegmental area; Addiction; Psychiatry; Dopaminergic","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001112576,0.0001073931,0.0001338683,0.0001734672,0.0004948237,0.00005608202,0.0005321442,0.00001563916,0.00003184944],"category_scores_gemma":[0.0001988754,0.00008986188,0.00002640569,0.001034811,0.0005619202,0.0002364015,0.00009343393,0.0001963371,0.00000116162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001912057,"about_ca_system_score_gemma":0.00004337073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009275429,"about_ca_topic_score_gemma":0.00005819211,"domain_scores_codex":[0.9977805,0.0006198112,0.000234803,0.0004834408,0.0005747426,0.0003066729],"domain_scores_gemma":[0.9992596,0.0004565381,0.00008240658,0.0001318794,0.000008415199,0.0000611772],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006835899,0.00005383198,0.03848562,0.000005526693,5.73162e-7,0.00003198605,0.0325607,0.0002566132,0.9222957,0.0001370152,0.00005954909,0.005429273],"study_design_scores_gemma":[0.001578034,0.001221374,0.7848958,0.00004954559,0.000009558452,0.0001179387,0.01413079,0.001077436,0.1894254,0.0005157605,0.006477428,0.0005009527],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960137,0.00009713996,0.000001803678,0.00335372,0.00009716309,0.0003288043,0.00006820676,0.00001885417,0.00002058776],"genre_scores_gemma":[0.998924,0.00001622919,0.00005485078,0.0009186747,0.00001442306,0.00004493705,2.005094e-7,0.000007684545,0.00001902335],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7464102,"threshold_uncertainty_score":0.3805834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02582838336588302,"score_gpt":0.2865399150573664,"score_spread":0.2607115316914834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}