{"id":"W4221062043","doi":"10.1158/1538-7445.sabcs21-gs2-07","title":"Abstract GS2-07: Updated results from a phase 3 randomized clinical trial in participants (pts) with 1-3 positive lymph nodes (LN), hormone receptor-positive (HR+) and HER2-negative (HER2-) breast cancer (BC) with recurrence score (RS) ≤ 25 randomized to endocrine therapy (ET) +/- chemotherapy (CT): SWOG S1007 (RxPONDER)","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre; BC Cancer Agency","funders":"","keywords":"Taxane; Medicine; Post-hoc analysis; Internal medicine; Oncology; Breast cancer; Clinical trial; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.008422742,0.0009390297,0.003637915,0.0006476146,0.0005959822,0.0001569362,0.0005986177,0.000149472,0.002478638],"category_scores_gemma":[0.001085739,0.0006694745,0.0003414667,0.002130957,0.002555882,0.0004674327,0.0002706665,0.002288754,0.00002552275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001810884,"about_ca_system_score_gemma":0.002814094,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03481241,"about_ca_topic_score_gemma":0.001411869,"domain_scores_codex":[0.9863492,0.005492632,0.001898529,0.002234209,0.00226281,0.001762662],"domain_scores_gemma":[0.9887128,0.007333701,0.0007974976,0.000952008,0.00128981,0.0009141932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9275772,0.002222504,0.0008631721,0.00002967743,0.00236538,0.000388196,0.006809665,0.0002502068,0.004421177,0.00004818321,0.0004138738,0.05461075],"study_design_scores_gemma":[0.9690314,0.003107517,0.01496479,0.00129589,0.0002211992,0.00007399097,0.001993194,0.0002697893,0.00722828,0.0002697584,0.0007330731,0.0008111222],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9636636,0.004429146,0.0002161062,0.01486349,0.0002735138,0.01283406,0.00335123,0.0001509692,0.0002178582],"genre_scores_gemma":[0.9750325,0.009546396,0.000919818,0.001530649,0.0005960805,0.0113,0.0004068489,0.0002559484,0.0004117555],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05379963,"threshold_uncertainty_score":0.9995757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08411709192082865,"score_gpt":0.4428197893327876,"score_spread":0.358702697411959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}