{"id":"W4221066105","doi":"10.1016/j.cjca.2022.03.009","title":"Differential Roles of Life-Course Cumulative Burden of Cardiovascular Risk Factors in Arterial Stiffness and Thickness","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Cardiovascular Health and Disease Prevention","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institute on Aging; National Institutes of Health; National Institute of General Medical Sciences; National Natural Science Foundation of China","keywords":"Medicine; Pulse wave velocity; Arterial stiffness; Blood pressure; Internal medicine; Cardiology; Body mass index; Cohort; Life course approach; Pulse pressure; Intima-media thickness; Carotid arteries","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001724078,0.0006796975,0.000615826,0.0006908492,0.0004801974,0.001569713,0.0009748288,0.001297327,0.003296921],"category_scores_gemma":[0.007077022,0.0007546886,0.001085794,0.0006931666,0.0005709621,0.001117129,0.000939597,0.001921839,0.0004438025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003758562,"about_ca_system_score_gemma":0.0006296203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006787552,"about_ca_topic_score_gemma":0.008034598,"domain_scores_codex":[0.9991452,0.000246954,0.00005223862,0.0002229773,0.0001113259,0.0002212035],"domain_scores_gemma":[0.9944936,0.001870404,0.001237791,0.000918014,0.0004423549,0.001037899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00130966,0.00009766442,0.9925827,0.00001599432,0.0003311029,0.0001652511,0.0002463622,0.0001646382,0.001343143,0.0001567197,0.00008035319,0.003506386],"study_design_scores_gemma":[0.000002739159,0.00004678098,0.9993944,0.000002886096,0.00003609356,0.00008697672,0.00008879374,0.0001715628,0.00005582225,0.00006600851,0.00004206048,0.000005825355],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971364,0.0009921576,0.0002435106,0.0001692716,0.00002390303,0.000005902708,0.0004204416,0.00001297148,0.0009953609],"genre_scores_gemma":[0.9986798,0.0001618521,0.0001446237,0.0000210268,0.00002962798,0.000003774585,0.0002930891,0.000008306696,0.0006577252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006787552,"threshold_uncertainty_score":0.01349604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01348006799808582,"score_gpt":0.2500535007148143,"score_spread":0.2365734327167285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}