{"id":"W4221081524","doi":"10.3389/fimmu.2022.838604","title":"Editorial: Generating and Sustaining Stable Autoantigen-Specific CD4 and CD8 Regulatory T Cells in Lupus","year":2022,"lang":"en","type":"editorial","venue":"Frontiers in Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"CD8; Systemic lupus erythematosus; Immunology; Biology; Medicine; Immune system; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00447207,0.004062346,0.002340502,0.002130426,0.002126069,0.003953956,0.002466696,0.008664498,0.02338375],"category_scores_gemma":[0.009138011,0.0008365116,0.001656489,0.0006482175,0.001427227,0.003044578,0.001066165,0.01152764,0.01662459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001774567,"about_ca_system_score_gemma":0.001459011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000610484,"about_ca_topic_score_gemma":0.001652677,"domain_scores_codex":[0.998068,0.000283007,0.0001963185,0.0003176224,0.0009441396,0.0001909142],"domain_scores_gemma":[0.993769,0.001775973,0.0004604499,0.0001607772,0.002096971,0.00173679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007031222,0.00001314255,0.00002202466,0.0001255774,0.0000108183,0.00009982598,0.000005678209,0.0000231939,0.000111443,0.0002247934,0.9950284,0.004264794],"study_design_scores_gemma":[0.0001241033,0.00006491754,0.0002974338,0.0002118867,0.00004935672,0.0003787497,0.0000307992,0.0001990822,0.0003612174,0.001355373,0.9969068,0.00002027576],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.0000683844,0.003546133,0.0001769107,0.02617434,0.9675771,0.000021705,0.00008775767,0.00009819699,0.002249407],"genre_scores_gemma":[0.0008530517,0.002917807,0.0001395305,0.01760392,0.9614802,0.00002451387,0.00006047664,0.00005599424,0.01686449],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.02338375,"threshold_uncertainty_score":0.07822639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005255271112181437,"score_gpt":0.2003484875408349,"score_spread":0.1950932164286535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}