{"id":"W4221082850","doi":"10.1016/j.ab.2022.114674","title":"Establishment and clinical application of time-resolved immunofluorescence assay of lipoprotein-associated phospholipase A2","year":2022,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Shanxi Provincial Key Research and Development Project; National Natural Science Foundation of China","keywords":"Nephelometry; Lipoprotein-associated phospholipase A2; Breast cancer; Phospholipase A2; Medicine; Lipoprotein; Lipoprotein(a); Antibody; Internal medicine; Chemistry; Cancer; Immunology; Cholesterol; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00248101,0.0005342519,0.0003881118,0.0006937602,0.0003108084,0.000724985,0.0004388416,0.0006701499,0.0009244962],"category_scores_gemma":[0.001653304,0.000267505,0.0002724417,0.0003228767,0.0006934756,0.0005059094,0.0003661589,0.001171317,0.0006707585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003286172,"about_ca_system_score_gemma":0.0007724054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00042264,"about_ca_topic_score_gemma":0.0004217771,"domain_scores_codex":[0.9989802,0.0003551321,0.00009557849,0.0002300023,0.0002460883,0.00009297169],"domain_scores_gemma":[0.9993035,0.0001848985,0.00007016843,0.0001216803,0.0002501924,0.00006957896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006985391,0.0002921906,0.006227186,0.0001791352,0.00002540009,0.0005706548,0.0001343723,0.0001664401,0.9431214,0.001519545,0.0005869165,0.04647819],"study_design_scores_gemma":[0.0001670879,0.004025661,0.0371879,0.00006005404,0.0002016788,0.006699085,0.0002690019,0.005678779,0.9122337,0.001522592,0.03191195,0.00004255696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.5151417,0.0425405,0.4134306,0.002822283,0.0007212346,0.001532904,0.0005251303,0.001074644,0.02221094],"genre_scores_gemma":[0.8984852,0.008203132,0.08631042,0.0006785107,0.0002621153,0.0007030878,0.0004921546,0.00006446432,0.004800813],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.00248101,"threshold_uncertainty_score":0.01312101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006433977958664,"score_gpt":0.2542512381649298,"score_spread":0.2478172602062658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}