{"id":"W4221087361","doi":"10.1101/2022.03.14.484356","title":"Atypical small GTPase RABL3 interacts with RAB11 to regulate early ciliogenesis in human cells","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Daiichi Sankyo Europe; Daiichi Sankyo Foundation of Life Science; York University; Japan Society for the Promotion of Science; Foundation for Promotion of Cancer Research; Mochida Memorial Foundation for Medical and Pharmaceutical Research; Nara Institute of Science and Technology; Foundation for Nara Institute of Science and Technology; Kurata Memorial Hitachi Science and Technology Foundation","keywords":"Ciliogenesis; Cilium; Centrosome; Centriole; Cell biology; Small GTPase; GTPase; Biology; Rab; Microtubule; Basal body; Genetics; Cell; Cell cycle; Gene; Flagellum; Signal transduction","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001444378,0.0001518353,0.0001951065,0.0002655603,0.0002870092,0.0003780338,0.0001211023,0.0003509953,0.001427227],"category_scores_gemma":[0.0001461845,0.0001553954,0.0003298932,0.0002073385,0.0001869426,0.00007266173,0.0002535257,0.0002605034,0.0006723448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005961629,"about_ca_system_score_gemma":0.0002274971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001641245,"about_ca_topic_score_gemma":0.001812517,"domain_scores_codex":[0.9998863,0.0000179112,0.000007523041,0.00002276162,0.00002905201,0.00003643396],"domain_scores_gemma":[0.9999368,0.00001266979,0.00001643998,0.00001003779,0.00001033647,0.00001360021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003332536,0.00001976247,0.001999783,0.00005523569,0.00001161362,0.000226302,0.00003282727,0.0001336182,0.9949074,0.0001396426,0.0004313848,0.001709141],"study_design_scores_gemma":[0.0000792827,0.0001104067,0.05819806,0.00001530188,0.00004219488,0.001122795,0.0001216941,0.004457014,0.9264246,0.0002261725,0.00918673,0.00001576001],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924951,0.002569076,0.001919786,0.0002340024,0.0000319034,0.00001629052,0.0008106137,0.0001796173,0.001743626],"genre_scores_gemma":[0.9967654,0.0004383998,0.0006872326,0.00009375921,0.000004689025,0.00001725247,0.0007417955,0.00001916497,0.001232423],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001641245,"threshold_uncertainty_score":0.00477457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009538275984581325,"score_gpt":0.2124542312095073,"score_spread":0.202915955224926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}