{"id":"W4221091889","doi":"10.1128/jvi.00255-22","title":"Impact of Early ARV Initiation on Relative Proportions of Effector and Regulatory CD8 T Cell in Mesenteric Lymph Nodes and Peripheral Blood During Acute SIV Infection of Rhesus Macaques","year":2022,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Université du Québec à Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Fonds de recherche du Québec; Canada Research Chairs; Government of Canada","keywords":"CD8; Biology; Simian immunodeficiency virus; Immunology; Cytotoxic T cell; Mesenteric lymph nodes; Lymph; T cell; Virology; Virus; Immune system; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001970561,0.0002415559,0.0005407543,0.0002438017,0.0002046432,0.0006080145,0.0001768202,0.0002902801,0.001314252],"category_scores_gemma":[0.0004446284,0.0001434287,0.0001778358,0.00009663651,0.0002641162,0.0002784414,0.0002290236,0.0007734958,0.0002779445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003008179,"about_ca_system_score_gemma":0.0002719603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001213542,"about_ca_topic_score_gemma":0.002152167,"domain_scores_codex":[0.9997541,0.00005163518,0.00001385534,0.00004981307,0.000033676,0.00009687453],"domain_scores_gemma":[0.9997143,0.0001060314,0.00003214024,0.00002329277,0.00004042158,0.00008378949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003515261,0.0001952104,0.005424547,0.0001322453,0.00001696072,0.0001358624,0.0003082396,0.0001252027,0.9826447,0.00006959213,0.00009992038,0.007332307],"study_design_scores_gemma":[0.0001620281,0.01128004,0.2512637,0.00009767088,0.0001558765,0.0004824104,0.001181972,0.001657622,0.7286234,0.0001762953,0.004877777,0.00004117142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981996,0.0009039175,0.0001086546,0.00002124094,0.00001253788,0.00001335725,0.0001560175,0.00001578465,0.0005689682],"genre_scores_gemma":[0.9977015,0.000331148,0.0003598379,0.00004492255,0.00001486685,0.00005221728,0.0003246132,0.000009873286,0.001161062],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001314252,"threshold_uncertainty_score":0.004396617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007481292520653588,"score_gpt":0.2679130331097949,"score_spread":0.2604317405891413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}