{"id":"W4221099083","doi":"10.1021/acs.jafc.1c06289","title":"Bioactive Peptides: From Basic Research to Clinical Trials and Commercialization","year":2022,"lang":"en","type":"review","venue":"Journal of Agricultural and Food Chemistry","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Commercialization; Hydrolysate; Clinical trial; Biotechnology; Medicine; Functional food; Pharmacology; Nutraceutical; Biology; Business; Biochemistry; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003012452,0.0003056256,0.001578029,0.00005379078,0.0001780688,0.0001028971,0.0003039872,0.0004196403,0.00005085742],"category_scores_gemma":[0.001503869,0.0001736857,0.0006135571,0.000213568,0.0001324039,0.00000989306,0.000401719,0.0007780309,0.000001072797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005125672,"about_ca_system_score_gemma":0.000141249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008941114,"about_ca_topic_score_gemma":0.000004061782,"domain_scores_codex":[0.9967257,0.001025402,0.001247447,0.0004338131,0.0003519958,0.0002155835],"domain_scores_gemma":[0.9977816,0.0004913184,0.001032119,0.0001758386,0.0002487298,0.0002704173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002204209,0.0002885143,0.00008294793,0.001760629,0.002686212,0.000008505065,0.0001096473,0.000001039446,0.04490034,0.000004415645,0.01069945,0.9392379],"study_design_scores_gemma":[0.0004121101,0.001022198,0.0002582748,0.001154532,0.0006286085,0.0001522927,0.0005109501,1.345689e-7,0.006736013,0.00003077409,0.9887682,0.00032595],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08321656,0.9158082,0.00000643327,0.000124688,0.0001245787,0.0003306196,0.0002503846,0.000002694059,0.0001358432],"genre_scores_gemma":[0.008856239,0.9882347,0.0001042351,0.00003590573,0.002229028,0.00003121274,0.0003123169,0.00001708032,0.0001792853],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9780687,"threshold_uncertainty_score":0.7082698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2644810057245935,"score_gpt":0.4585070757600384,"score_spread":0.1940260700354449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}