{"id":"W4221099817","doi":"10.1158/1538-7445.sabcs21-ot2-21-01","title":"Abstract OT2-21-01: A randomized, multicenter pragmatic trial comparing bone pain from a single dose of pegfilgrastim to 5 doses of daily filgrastim in breast cancer patients receiving neoadjuvant/adjuvant chemotherapy (REaCT-5G)","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Neutropenia and Cancer Infections","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Pegfilgrastim; Medicine; Filgrastim; Breast cancer; Bone pain; Chemotherapy; Neutropenia; Febrile neutropenia; Randomized controlled trial; Surgery; Multicenter trial; Oncology; Internal medicine; Cancer; Multicenter study","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003469487,0.002253938,0.003826637,0.0005098184,0.0006882354,0.001760722,0.001159735,0.003044306,0.01664916],"category_scores_gemma":[0.004652071,0.0008269768,0.003707297,0.0006064628,0.001577883,0.001510403,0.0009423358,0.003995034,0.001626227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00139184,"about_ca_system_score_gemma":0.001730615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001651034,"about_ca_topic_score_gemma":0.002522784,"domain_scores_codex":[0.9977764,0.001504672,0.0001291051,0.0002894643,0.00009795241,0.0002023085],"domain_scores_gemma":[0.9972274,0.0008646647,0.0006601067,0.0001491736,0.000199959,0.0008986307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9860672,0.004115756,0.0002552561,0.0009573998,0.001231805,0.00002939309,0.00003292627,0.0001780402,0.0006234352,0.00009134287,0.0006391832,0.005778247],"study_design_scores_gemma":[0.9676442,0.03072273,0.000520175,0.00005002565,0.0004508689,0.0000122923,0.00001915192,0.0001479941,0.00005062851,0.0000867297,0.0002862169,0.000008953302],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9549906,0.009249771,0.00119072,0.003878518,0.002363028,0.02017454,0.002964447,0.0002140296,0.004974294],"genre_scores_gemma":[0.9692208,0.002186398,0.002679155,0.003622224,0.001207767,0.01532749,0.001923712,0.00003559516,0.003796935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01664916,"threshold_uncertainty_score":0.05569696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04701009547556543,"score_gpt":0.364894265693216,"score_spread":0.3178841702176505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}