{"id":"W4221100608","doi":"10.3390/curroncol29030163","title":"The Role of the 21-Gene Recurrence Score® Assay in Hormone Receptor-Positive, Node-Positive Breast Cancer: The Canadian Experience","year":2022,"lang":"en","type":"review","venue":"Current Oncology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Université de Montréal; Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé","keywords":"Medicine; Breast cancer; Hormone receptor; Oncology; Gene; Internal medicine; Receptor; Bioinformatics; Cancer; Cancer research; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002161545,0.0006101316,0.001227845,0.002939636,0.0002843471,0.001199999,0.001009774,0.0009621406,0.001192358],"category_scores_gemma":[0.003520072,0.0002334733,0.0006893862,0.003459178,0.0008157087,0.0006387204,0.0004360651,0.001847339,0.0004240487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00419732,"about_ca_system_score_gemma":0.006880453,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.08119451,"about_ca_topic_score_gemma":0.1355011,"domain_scores_codex":[0.9994087,0.0001267862,0.00007147207,0.00007504021,0.0002714201,0.0000466371],"domain_scores_gemma":[0.9974658,0.001223243,0.0001584023,0.00003809203,0.001005501,0.0001089376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0001438862,0.00002843988,0.000871357,0.0129407,0.0001968851,0.0001518111,0.00008001539,0.0003148628,0.0005208778,0.002040002,0.0316061,0.9511051],"study_design_scores_gemma":[0.00004246164,0.0001290633,0.005511167,0.01237006,0.0006055929,0.001201078,0.0001030455,0.0001608645,0.0006390586,0.001005098,0.978187,0.00004548891],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000731724,0.9990968,0.00002971645,0.0003247704,0.00008032668,0.00000196534,0.00001563817,0.000001479361,0.0003761129],"genre_scores_gemma":[0.0008598777,0.9985398,0.0000881884,0.0002370461,0.00007010358,0.00000224162,0.00002685586,0.000001134862,0.0001747097],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9188055,"threshold_uncertainty_score":0.1614438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04593806074562057,"score_gpt":0.3545899193370519,"score_spread":0.3086518585914313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}