{"id":"W4221104422","doi":"10.6004/jnccn.2021.7268","title":"CLO22-052: A Tale of Two Schedules: A Study of the Efficacy and Toxicity Outcomes of Extended Durvalumab Dosing in Patients with Stage III Unresectable Non-Small Cell Lung Cancer (NSCLC)","year":2022,"lang":"en","type":"article","venue":"Journal of the National Comprehensive Cancer Network","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Medicine; Durvalumab; Dosing; Toxicity; Oncology; Stage (stratigraphy); Internal medicine; Lung cancer; non-small cell lung cancer (NSCLC); Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001841449,0.0008592813,0.00149733,0.0003273526,0.000343063,0.0008732125,0.0006724125,0.0009235483,0.002389079],"category_scores_gemma":[0.0009990818,0.0003744817,0.001244283,0.0003505295,0.0005365653,0.0008268979,0.0003342133,0.002565342,0.0003725661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008925378,"about_ca_system_score_gemma":0.001276538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001788853,"about_ca_topic_score_gemma":0.005499658,"domain_scores_codex":[0.9994695,0.0002718827,0.00002284453,0.00007079165,0.00007747001,0.00008754951],"domain_scores_gemma":[0.9992942,0.0001398869,0.000121165,0.00005306153,0.00004044426,0.0003512285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6975866,0.06409843,0.01874993,0.0006313996,0.003490859,0.000344056,0.0005101634,0.002158622,0.03786796,0.0004641124,0.006640414,0.1674575],"study_design_scores_gemma":[0.3229409,0.6391416,0.02590468,0.0000385461,0.001465133,0.0002800668,0.0001072703,0.001389199,0.003462553,0.0001153677,0.005075557,0.00007921087],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961929,0.001302721,0.0001735204,0.0003851669,0.00008367737,0.0003990681,0.0005493734,0.00002551072,0.0008880596],"genre_scores_gemma":[0.9922145,0.001772572,0.0006985665,0.0009996459,0.0002039014,0.0005171766,0.001139149,0.00002574397,0.002428615],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002389079,"threshold_uncertainty_score":0.009738684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02001176707144655,"score_gpt":0.3049283032698555,"score_spread":0.284916536198409,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}