{"id":"W4221112432","doi":"10.1016/s0735-1097(22)02095-2","title":"THE EPIGENETIC BET-INHIBITOR APABETALONE REDUCES CARDIOVASCULAR EVENTS IN PATIENTS WITH TYPE 2 DIABETES, ACUTE CORONARY SYNDROME AND AN ELEVATED ANGULO NON-ALCOHOLIC FATTY LIVER DISEASE FIBROSIS SCORE - EXPLORATORY ANALYSIS OF THE BETONMACE TRIAL","year":2022,"lang":"en","type":"article","venue":"Journal of the American College of Cardiology","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Resverlogix (Canada)","funders":"","keywords":"Medicine; Type 2 diabetes; Fatty liver; Internal medicine; Acute coronary syndrome; Gastroenterology; Steatohepatitis; Diabetes mellitus; Fibrosis; Disease; Cardiology; Endocrinology; Myocardial infarction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008840254,0.0009064582,0.001486712,0.0001770504,0.000193154,0.0008602287,0.0004198247,0.0005177845,0.002527385],"category_scores_gemma":[0.001265079,0.0002991277,0.001478774,0.0002501875,0.0004192447,0.0005428999,0.0004352527,0.001611,0.0003080175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003393879,"about_ca_system_score_gemma":0.0003343487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006373,"about_ca_topic_score_gemma":0.002550458,"domain_scores_codex":[0.9996928,0.0001615879,0.00001584382,0.00004757344,0.00002907225,0.00005317587],"domain_scores_gemma":[0.9995883,0.0001106649,0.0001204481,0.00005130601,0.00002224214,0.0001070229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8927517,0.003336438,0.02482962,0.001239514,0.01336248,0.0001278307,0.00009083415,0.001294772,0.006683146,0.0004899964,0.001688078,0.0541056],"study_design_scores_gemma":[0.7086182,0.07392712,0.1847317,0.0003064401,0.021733,0.0003199282,0.0002489692,0.002588461,0.001394287,0.002126687,0.003914908,0.00009014366],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991623,0.005763829,0.0001554135,0.0005002043,0.0001473287,0.00008426466,0.0003465278,0.00002263473,0.001356877],"genre_scores_gemma":[0.9962071,0.001684831,0.0002237886,0.0004432011,0.0001838847,0.00007286765,0.0004583251,0.00000551007,0.0007204908],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002527385,"threshold_uncertainty_score":0.008454919,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009646353649492385,"score_gpt":0.2310016055497598,"score_spread":0.2213552519002674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}