{"id":"W4221114436","doi":"10.1101/2022.03.30.486436","title":"Obligate sexual reproduction of a homothallic fungus closely related to the <i>Cryptococcus</i> pathogenic species complex","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Yeasts and Rust Fungi Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Human Genome Research Institute; National Institutes of Health; Deutsche Forschungsgemeinschaft; North Carolina State University; National Institute of Allergy and Infectious Diseases; Broad Institute; Canadian Institute for Advanced Research","keywords":"Biology; Homothallism; Mating type; Heterothallic; Sexual reproduction; Obligate; Cryptococcus neoformans; Genetics; Cryptococcus; Cryptococcus gattii; Synteny; Basidium; Evolutionary biology; Gene; Genome; Hypha; Microbiology; Botany","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004231769,0.0002151395,0.000104506,0.0002727599,0.0002541714,0.0002682454,0.0001463979,0.0001998352,0.0004157178],"category_scores_gemma":[0.00007209996,0.00007244435,0.0001405899,0.0001918501,0.0001228559,0.0000854566,0.0002321979,0.0002599776,0.000111965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001820186,"about_ca_system_score_gemma":0.0001471914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001733119,"about_ca_topic_score_gemma":0.001627519,"domain_scores_codex":[0.9999088,0.000007470626,0.000008065087,0.00003260916,0.00001796626,0.0000250027],"domain_scores_gemma":[0.9999068,0.00000984603,0.00004026172,0.00001177481,0.000009122361,0.00002218056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002038645,0.000008490356,0.002087165,0.00001120426,0.000002532675,0.0001039621,0.00001427044,0.00001608764,0.9970508,0.00004082073,0.00001540004,0.0006288658],"study_design_scores_gemma":[0.00001193608,0.0002968042,0.2576073,0.00001349734,0.00003478125,0.006922822,0.0002817151,0.00162145,0.728579,0.000152057,0.004460882,0.00001777867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984162,0.0001620549,0.0005114489,0.00001966823,0.000003346538,0.00001223658,0.0002117999,0.00001673789,0.0006465196],"genre_scores_gemma":[0.9977778,0.00008163739,0.001183188,0.00003105819,0.000002269986,0.000006164586,0.0004795013,0.000004998823,0.0004334626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001733119,"threshold_uncertainty_score":0.003446102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.017567698288192,"score_gpt":0.230066655215049,"score_spread":0.212498956926857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}