{"id":"W4221115800","doi":"10.1101/2022.03.18.484874","title":"Per-Pathogen Virulence of HIV-1 subtypes A, C and D","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Virulence; Pathogen; Viral load; Biology; Virology; Human immunodeficiency virus (HIV); Immunology; Cd4 t cell; Set point; Lentivirus; Viral disease; T cell; Genetics; Immune system; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001361054,0.0002776781,0.0003049332,0.0007496514,0.0002894519,0.0008161779,0.0005690815,0.0004670061,0.002639255],"category_scores_gemma":[0.003996475,0.0001546893,0.0006874157,0.0005504613,0.0002858832,0.0003664671,0.000411323,0.0005794557,0.0002993916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004571841,"about_ca_system_score_gemma":0.0004070167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006060908,"about_ca_topic_score_gemma":0.002829317,"domain_scores_codex":[0.9991358,0.0003525517,0.00007247359,0.0001664655,0.0001634712,0.0001093354],"domain_scores_gemma":[0.995184,0.002319374,0.001096538,0.0006532868,0.0004198556,0.0003269929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003905272,0.00008785153,0.9733521,0.00004085047,0.0001835929,0.0001088298,0.0001183175,0.004109827,0.0138449,0.0004577264,0.000190593,0.007114855],"study_design_scores_gemma":[0.00001923273,0.0003378633,0.972525,0.00001750173,0.00006700704,0.0005511678,0.0003045362,0.02167642,0.003269818,0.0008258872,0.0003822465,0.00002324186],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997724,0.00013501,0.0009457843,0.00003618682,0.00000452945,0.00001074734,0.0005984787,0.00001254161,0.0005327358],"genre_scores_gemma":[0.9986002,0.00003170215,0.000703621,0.00001167294,0.000003109308,0.00000496516,0.0004901395,0.000003373439,0.0001512659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006060908,"threshold_uncertainty_score":0.01205122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01280729537894398,"score_gpt":0.2285186963894967,"score_spread":0.2157114010105527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}