{"id":"W4221122007","doi":"10.1111/acel.13597","title":"Müller Glia maintain their regenerative potential despite degeneration in the aged zebrafish retina","year":2022,"lang":"en","type":"article","venue":"Aging Cell","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Office of Extramural Research, National Institutes of Health; Biotechnology and Biological Sciences Research Council; University of Sheffield; Medical Research Council; Royal Society of Canada; National Eye Institute; Wellcome Trust","keywords":"Zebrafish; Biology; Retina; Muller glia; Degeneration (medical); Regeneration (biology); Cell biology; Neuroscience; Retinal degeneration; Anatomy; Physiology; Pathology; Stem cell; Genetics; Progenitor cell","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004716719,0.0001192147,0.00007324316,0.00004033085,0.0002808706,0.00004147741,0.0002263124,0.00003880685,0.00007109668],"category_scores_gemma":[0.00001377759,0.00009595467,0.00005680505,0.0001338839,0.0000306945,0.000003931566,0.0001293617,0.000146545,0.000004219988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002167976,"about_ca_system_score_gemma":0.00005248876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002533823,"about_ca_topic_score_gemma":0.00006885432,"domain_scores_codex":[0.9989379,0.0003024873,0.0001464776,0.0002623668,0.0001456519,0.0002050978],"domain_scores_gemma":[0.9996954,0.00001018855,0.00005817138,0.0001940942,0.00002043899,0.00002175473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009305093,0.00008993383,0.005361297,0.000007308942,0.00001328475,0.00002718472,0.001890004,0.002005538,0.9681881,0.0001993405,0.02148461,0.000640344],"study_design_scores_gemma":[0.00203408,0.0004499306,0.01670649,0.000009376547,0.00002509168,0.00004029383,0.01030275,0.001159414,0.8953267,0.00126396,0.07196216,0.0007197918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946874,0.000348833,0.001045203,0.0008382847,0.0001500053,0.0001992916,0.000005431618,0.000008337459,0.002717223],"genre_scores_gemma":[0.9963589,0.00003682536,0.0004521124,0.001345578,0.0001053568,0.00005794786,0.0003977347,0.00001457235,0.00123099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07286145,"threshold_uncertainty_score":0.3912918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005657966765629877,"score_gpt":0.2022086709077821,"score_spread":0.1965507041421522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}