{"id":"W4221137432","doi":"10.1038/s42003-022-03143-z","title":"Overall structure of fully assembled cyanobacterial KaiABC circadian clock complex by an integrated experimental-computational approach","year":2022,"lang":"en","type":"article","venue":"Communications Biology","topic":"Photosynthetic Processes and Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Japan Society for the Promotion of Science; Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences; Japan Atomic Energy Agency; Ministry of Education, Culture, Sports, Science and Technology; Japan Agency for Medical Research and Development","keywords":"Biological system; Circadian clock; Matching (statistics); Biology; Physics; Statistical physics; Circadian rhythm; Mathematics; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001171035,0.0001487948,0.0001943239,0.00005449706,0.0002886415,0.00001333898,0.001066756,0.0001206879,0.0002092255],"category_scores_gemma":[0.00002055396,0.0001535795,0.00006187049,0.0001107129,0.0001381076,0.000005556467,0.0006264546,0.0001624354,9.20646e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003589677,"about_ca_system_score_gemma":0.0001529702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007903598,"about_ca_topic_score_gemma":0.00001402624,"domain_scores_codex":[0.9988021,0.0003643578,0.0002741343,0.0002994909,0.00007444031,0.0001854433],"domain_scores_gemma":[0.9987212,0.00001844818,0.0001700781,0.000925286,0.00009509309,0.00006982645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007763127,0.0003585941,0.00007449458,0.000004400533,0.000045299,7.022047e-8,0.0001236962,0.0002060121,0.993291,0.005317575,0.0002418652,0.0002594287],"study_design_scores_gemma":[0.001090171,0.0009978161,0.0001498209,0.00000257726,0.00002128769,0.0000528222,0.0007293712,0.005274008,0.884276,0.002264845,0.1048223,0.000318997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901995,0.0003923079,0.007387718,0.0001237771,0.000103368,0.0002554231,0.0008524447,0.00002019974,0.000665257],"genre_scores_gemma":[0.9770899,0.0000380164,0.007192617,0.0003282728,0.00002876233,0.0000764272,0.01519257,0.000019404,0.00003406716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.109015,"threshold_uncertainty_score":0.6262792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.023313442109378,"score_gpt":0.2907781170536364,"score_spread":0.2674646749442584,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}