{"id":"W4223412519","doi":"10.3390/cells11071235","title":"Two Different Therapeutic Approaches for SARS-CoV-2 in hiPSCs-Derived Lung Organoids","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Leibniz-Gemeinschaft; Fondazione Roma; Deutsches Primatenzentrum","keywords":"Dipeptidyl peptidase-4; Organoid; Induced pluripotent stem cell; In vitro; Biology; Innate immune system; Receptor; Humanized mouse; Lung; In vivo; Immunology; Virology; Medicine; Immune system; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002172395,0.0003127339,0.000392942,0.0002293007,0.0001561474,0.0003506737,0.00022745,0.0004335867,0.0009436021],"category_scores_gemma":[0.00008867285,0.0001020481,0.0004705561,0.0001523222,0.0002485316,0.0001851933,0.00027537,0.0007942682,0.000342102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002144489,"about_ca_system_score_gemma":0.0002629666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005715954,"about_ca_topic_score_gemma":0.0009860614,"domain_scores_codex":[0.9997885,0.00002783541,0.0000276292,0.0000482335,0.00006762145,0.00004022534],"domain_scores_gemma":[0.9999051,0.00001612134,0.0000217752,0.00001730024,0.00001353727,0.00002601904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001192342,0.0000691296,0.0002057714,0.0001166053,0.00001096089,0.0001303617,0.00005027933,0.000227816,0.9960532,0.0001747486,0.00007688339,0.002765075],"study_design_scores_gemma":[0.00002474544,0.0006225519,0.001382129,0.000009810855,0.00003137459,0.0002797261,0.00004501962,0.0004875032,0.9936017,0.00003122307,0.003476323,0.000007796343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9710298,0.00428634,0.01836265,0.0001852464,0.0001730592,0.0003389844,0.001252238,0.0002791366,0.004092501],"genre_scores_gemma":[0.9826584,0.001662965,0.01136002,0.00013395,0.00001616101,0.0002335422,0.0009334642,0.00002351196,0.002978037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009436021,"threshold_uncertainty_score":0.003156662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1551315654701911,"score_gpt":0.3864711630403198,"score_spread":0.2313395975701286,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}