{"id":"W4223412519","doi":"10.3390/cells11071235","title":"Two Different Therapeutic Approaches for SARS-CoV-2 in hiPSCs-Derived Lung Organoids","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Leibniz-Gemeinschaft; Fondazione Roma; Deutsches Primatenzentrum","keywords":"Dipeptidyl peptidase-4; Organoid; Induced pluripotent stem cell; In vitro; Biology; Innate immune system; Receptor; Humanized mouse; Lung; In vivo; Immunology; Virology; Medicine; Immune system; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004832201,0.0001543255,0.0003157994,0.0001959321,0.0001447698,0.00001365992,0.0002017349,0.00004700248,0.0002199138],"category_scores_gemma":[0.00004516279,0.00013519,0.00008191901,0.0002717884,0.00005995265,0.00003125945,0.0001624034,0.0004865518,0.00002565876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004824426,"about_ca_system_score_gemma":0.0002780718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003335237,"about_ca_topic_score_gemma":0.0000222288,"domain_scores_codex":[0.9982277,0.0001760349,0.0002797529,0.0003564065,0.0004444332,0.0005156936],"domain_scores_gemma":[0.9992018,0.0002364758,0.00005192021,0.0003632943,0.00003612863,0.0001103586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008561641,0.0004582083,0.002162487,0.0008757598,0.00003832202,0.00005551325,0.0006342927,0.00001654863,0.9516774,0.0004154052,0.00077902,0.04203086],"study_design_scores_gemma":[0.006231021,0.0008230454,0.004174982,0.00003914486,0.00003862758,0.00001363145,0.0006131335,0.005821923,0.9108955,0.0005112975,0.07058118,0.0002564611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918454,0.003620793,0.0003285006,0.001245969,0.000222115,0.001980493,0.00002336222,0.00004692825,0.0006864256],"genre_scores_gemma":[0.9960147,0.0000439784,0.000181294,0.002200274,0.00009928334,0.0006104439,0.00002674121,0.00005425151,0.0007690323],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06980217,"threshold_uncertainty_score":0.5512886,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1551315654701911,"score_gpt":0.3864711630403198,"score_spread":0.2313395975701286,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}