{"id":"W4223420165","doi":"10.1038/s41420-022-00998-3","title":"Cell pyroptosis in health and inflammatory diseases","year":2022,"lang":"en","type":"article","venue":"Cell Death Discovery","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"National Natural Science Foundation of China","keywords":"Pyroptosis; Inflammation; Proinflammatory cytokine; Immunology; Medicine; Cancer; Programmed cell death; Mechanism (biology); Inflammasome; Biology; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005796427,0.0004272578,0.0006835705,0.001117622,0.0003558036,0.0009608421,0.0003750233,0.001104372,0.001920647],"category_scores_gemma":[0.0004158244,0.0001183091,0.0003268253,0.0009016173,0.0009066132,0.001151378,0.0008245843,0.001526495,0.0008284623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006874963,"about_ca_system_score_gemma":0.0006484109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003505799,"about_ca_topic_score_gemma":0.0004383056,"domain_scores_codex":[0.9996437,0.00008829112,0.00005564958,0.00005348349,0.0001131099,0.0000457489],"domain_scores_gemma":[0.9997763,0.00006197375,0.00004710647,0.00001000254,0.00006353775,0.00004118048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004595958,0.000147,0.002948879,0.01292999,0.0001469124,0.003448914,0.0008642919,0.0006502953,0.04989683,0.08368785,0.05883038,0.7859891],"study_design_scores_gemma":[0.00002764005,0.0002992482,0.003596422,0.001651559,0.00007677051,0.008321874,0.000325727,0.0002414746,0.007758759,0.02839023,0.9492715,0.00003887458],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001602614,0.991557,0.001033596,0.001926196,0.0009716355,0.00001009758,0.00003380849,0.00001887646,0.002846305],"genre_scores_gemma":[0.02389693,0.9663641,0.001650653,0.001698953,0.00226,0.00002791576,0.00009426288,0.000006963828,0.004000203],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001920647,"threshold_uncertainty_score":0.006425202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004519590993157046,"score_gpt":0.2051182170952024,"score_spread":0.2005986261020454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}