{"id":"W4223420165","doi":"10.1038/s41420-022-00998-3","title":"Cell pyroptosis in health and inflammatory diseases","year":2022,"lang":"en","type":"article","venue":"Cell Death Discovery","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"National Natural Science Foundation of China","keywords":"Pyroptosis; Inflammation; Proinflammatory cytokine; Immunology; Medicine; Cancer; Programmed cell death; Mechanism (biology); Inflammasome; Biology; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001009261,0.0001305906,0.0001299058,0.00006179212,0.0001626541,0.00003150949,0.0001349803,0.00003475392,0.00002769784],"category_scores_gemma":[0.00001043098,0.0001405199,0.000064634,0.00007031189,0.00003768528,0.00001171233,0.0002898395,0.0001079204,0.000003760037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002963553,"about_ca_system_score_gemma":0.0002006617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004399259,"about_ca_topic_score_gemma":0.000006914401,"domain_scores_codex":[0.9990436,0.00009241068,0.0002033597,0.0002890033,0.000105926,0.0002657191],"domain_scores_gemma":[0.9995893,0.00000792157,0.00007459366,0.0002456702,0.000008200092,0.00007426988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007021714,0.0009334424,0.6970583,0.0007320915,0.00005071851,0.00004466315,0.001237762,0.00222176,0.2802647,0.0005559464,0.01422438,0.001974046],"study_design_scores_gemma":[0.00847023,0.002994287,0.1939751,0.00007495493,0.00005754398,0.00002283686,0.01408323,0.0002727165,0.2174602,0.0008108543,0.5595911,0.002186956],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806896,0.01665726,0.00003078708,0.00007505745,0.0001118663,0.0001731094,0.00004082984,0.000007798298,0.002213671],"genre_scores_gemma":[0.9946383,0.00166155,0.00002107098,0.0007639981,0.00003710032,0.00006488257,0.000260802,0.00002209148,0.002530263],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5453667,"threshold_uncertainty_score":0.5730237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004519590993157046,"score_gpt":0.2051182170952024,"score_spread":0.2005986261020454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}