{"id":"W4223437636","doi":"10.1002/ijc.34018","title":"Abiraterone acetate plus prednisolone for metastatic patients starting hormone therapy: 5‐year follow‐up results from the STAMPEDE randomised trial (NCT00268476)","year":2022,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Janssen Research and Development; Medical Research Council; Takeda Oncology; Medical Research Council Canada; Astellas Pharma; University College London; Royal Marsden NHS Foundation Trust; Department of Health and Social Care; Cancer Research UK; Clovis Oncology; BeiGene; Abbott Laboratories; Schweizerische Arbeitsgemeinschaft für Klinische Krebsforschung; Sanofi; National Institute for Health and Care Research; Novartis; Pfizer","keywords":"Medicine; Abiraterone acetate; Prednisolone; Internal medicine; Androgen deprivation therapy; Proportional hazards model; Prostate cancer; Hazard ratio; Surgery; Oncology; Confidence interval; Cancer","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004094837,0.0007451866,0.001898335,0.0003420253,0.0003446941,0.001076755,0.0005285192,0.001140722,0.005003226],"category_scores_gemma":[0.004551687,0.0002750941,0.002607338,0.0006189718,0.0006566506,0.0005586732,0.0004111751,0.001410171,0.0004296078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008105155,"about_ca_system_score_gemma":0.001235195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001635516,"about_ca_topic_score_gemma":0.003716237,"domain_scores_codex":[0.9981522,0.001125728,0.000143253,0.0002308103,0.0002006899,0.0001472221],"domain_scores_gemma":[0.9970257,0.001269197,0.0008231079,0.0002538914,0.0001789258,0.0004492534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9701843,0.0009138829,0.00724499,0.000818831,0.002558456,0.00007263758,0.00005871711,0.0005423122,0.000832176,0.0001417225,0.001273456,0.01535863],"study_design_scores_gemma":[0.8432862,0.09752452,0.0480144,0.0003358611,0.005718376,0.0001957312,0.0001155429,0.001023491,0.000486636,0.0005016139,0.00273216,0.00006543074],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867225,0.00712831,0.0003031225,0.0004172351,0.0002876774,0.00045191,0.002894334,0.00002583335,0.001768987],"genre_scores_gemma":[0.9920305,0.002101443,0.0003055033,0.0002966645,0.0002887277,0.0005887802,0.003203781,0.000006183455,0.001178432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005003226,"threshold_uncertainty_score":0.02165586,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0600295178885569,"score_gpt":0.3658253147122705,"score_spread":0.3057957968237136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}