{"id":"W4223450638","doi":"10.1159/000524552","title":"C3 Glomerulopathy: A Review with Emphasis on Ultrastructural Features","year":2022,"lang":"en","type":"review","venue":"Glomerular Diseases","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Glomerulopathy; Alternative complement pathway; Membranoproliferative glomerulonephritis; Complement system; Complement membrane attack complex; Pathology; Immunofluorescence; Autoantibody; C3-convertase; Negative stain; Antibody; Chemistry; Complement (music); Glomerulonephritis; Cell biology; Biology; Immunology; Medicine; Kidney; Electron microscope; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.0001863659,0.001284007,0.003363887,0.0004126469,0.0005682922,0.00006279404,0.001197015,0.0002315412,0.01881396],"category_scores_gemma":[0.0002961293,0.0009118816,0.001478735,0.0008509441,0.0002759149,0.0001070784,0.0003255173,0.0007078796,0.001199432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003570181,"about_ca_system_score_gemma":0.0006581984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003752152,"about_ca_topic_score_gemma":0.000005828872,"domain_scores_codex":[0.994874,0.001495214,0.001021196,0.001364228,0.0003425642,0.000902818],"domain_scores_gemma":[0.9966016,0.000603782,0.000874925,0.001684101,0.0000672308,0.0001684023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000970959,0.0002940252,0.00007964533,0.06081355,0.001808317,0.0001768156,0.00001547643,6.629007e-7,0.000001134406,0.0001327543,0.0639905,0.87259],"study_design_scores_gemma":[0.0005806924,0.0003199289,0.0002442906,0.03814277,0.007844656,0.0005848434,0.00004842533,9.579566e-9,0.000001661766,0.00001003774,0.951238,0.0009846758],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002236323,0.9880288,9.549948e-7,0.00005691743,0.0009315645,0.003042397,0.006826289,0.0003519119,0.0007387878],"genre_scores_gemma":[0.00008623301,0.983506,0.00001043856,0.0005076749,0.0001376743,0.0019871,0.01235562,0.0001655764,0.001243631],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8872475,"threshold_uncertainty_score":0.9999912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0271721871455683,"score_gpt":0.3080335494197734,"score_spread":0.2808613622742051,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}