{"id":"W4223479604","doi":"10.1111/tan.14623","title":"Next‐generation sequencing identifies two novel HLA class II alleles, <i>HLA‐DRB1*01:115</i> and <i>HLA‐DRB1*14:224</i>","year":2022,"lang":"en","type":"article","venue":"HLA","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"","keywords":"Human leukocyte antigen; HLA-DRB1; Allele; Genetics; Biology; Class (philosophy); HLA-A; Gene; Antigen; Computer science; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001235595,0.0002628779,0.0001661675,0.0003397198,0.0001897326,0.000339951,0.0001903004,0.0004765842,0.001358002],"category_scores_gemma":[0.0004028147,0.00009306141,0.0002938047,0.000157327,0.0001556537,0.00007427486,0.0001620469,0.0004183309,0.0003766848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001506794,"about_ca_system_score_gemma":0.0001233986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001077835,"about_ca_topic_score_gemma":0.001672686,"domain_scores_codex":[0.9998761,0.00001177478,0.00001212307,0.00003664878,0.00003253991,0.00003072373],"domain_scores_gemma":[0.999768,0.00007117013,0.00005090827,0.00001880567,0.00002615083,0.00006502809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003176832,0.00009348157,0.05120082,0.00007273974,0.0000590224,0.002450278,0.0002072479,0.0002604314,0.9237691,0.0002743024,0.0007224768,0.02057239],"study_design_scores_gemma":[0.0001743297,0.0008837717,0.4619123,0.00008948231,0.0004221348,0.02696073,0.000543447,0.006866015,0.4733229,0.00118163,0.0275789,0.00006422565],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938523,0.0003660645,0.003105295,0.0001632631,0.00004462952,0.00002732382,0.000796826,0.00004072914,0.001603545],"genre_scores_gemma":[0.9925488,0.0001829496,0.004303752,0.0002751854,0.00001962296,0.00002228574,0.001290068,0.00001692102,0.001340329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001358002,"threshold_uncertainty_score":0.004542947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03683909887863064,"score_gpt":0.2327633583335456,"score_spread":0.1959242594549149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}