{"id":"W4223479604","doi":"10.1111/tan.14623","title":"Next‐generation sequencing identifies two novel HLA class II alleles, <i>HLA‐DRB1*01:115</i> and <i>HLA‐DRB1*14:224</i>","year":2022,"lang":"en","type":"article","venue":"HLA","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"","keywords":"Human leukocyte antigen; HLA-DRB1; Allele; Genetics; Biology; Class (philosophy); HLA-A; Gene; Antigen; Computer science; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006932058,0.0005285686,0.0006615013,0.0002560257,0.002111358,0.00012243,0.0005961753,0.0004188552,0.001441788],"category_scores_gemma":[0.0000727106,0.0005383174,0.0002035879,0.0003414009,0.0005221146,0.0003718454,0.001047023,0.001167725,0.0003419463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002266666,"about_ca_system_score_gemma":0.0002350598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009481028,"about_ca_topic_score_gemma":0.0007366905,"domain_scores_codex":[0.9966601,0.0004801298,0.0007678407,0.0009842539,0.0001475128,0.000960202],"domain_scores_gemma":[0.9985452,0.0001914261,0.0003534387,0.0007235109,0.0001191677,0.00006724787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001430308,0.0002586143,0.0001850055,0.00002780833,0.0002233027,0.00003679299,0.001246948,0.0001501033,0.9513319,0.002959967,0.04100634,0.002430187],"study_design_scores_gemma":[0.00408081,0.0005099375,0.00009217309,0.00002774459,0.0001663494,0.0009511649,0.001769972,0.0002500646,0.452844,0.0004387698,0.5380856,0.0007833868],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9700156,0.01715825,0.0006442706,0.001898339,0.004800971,0.0006037494,0.0001969285,0.0003463352,0.004335522],"genre_scores_gemma":[0.9659109,0.0007116472,0.0002164887,0.002113028,0.0002730899,0.0001599526,0.0009474216,0.00007507166,0.02959239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4984879,"threshold_uncertainty_score":0.9997069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03683909887863064,"score_gpt":0.2327633583335456,"score_spread":0.1959242594549149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}